DIAGNOSTIC ACCURACY OF DIFFUSION WEIGHTED MRI IN DIFFERENTIATING WHO GRADE-1 FROM HIGH-GRADE MENINGIOMAS
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2017, Vol 6, Issue 38
Abstract
BACKGROUND The aim is to study the diagnostic accuracy of diffusion weighted magnetic resonance imaging in differentiating WHO Grade-1, from high-grade meningiomas and comparing with histopathology as the gold standard. MATERIALS AND METHODS 100 patients with intracranial meningiomas referred to the Department of Radiodiagnosis for imaging were included in the study after applying inclusion and exclusion criteria. MR imaging of the head with diffusion weighted imaging was done. ADC was calculated with B value of 0 - 1000. Cut-off was obtained after drawing ROC for ADC values. RESULTS Using ADC value as the diagnostic test, present study shows a sensitivity of 90.48% and specificity of 98.73% (p < 0.0001) for differentiating Grade-1 and high-grade meningiomas. CONCLUSION Diffusion weighted imaging in the tumour can reliably differentiate between WHO Grade-1 and high-grade meningiomas.
Authors and Affiliations
Rani Ann Joseph, Anusha Lingaiah Pujar, Manoj Thankappan Pillai
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