Fast Dissolving Tablet- A Review
Journal Title: The Pharma Innovation - Year 2012, Vol 1, Issue 1
Abstract
The convenience of administration and improved patient compliance are important in the design of oral drug delivery system which remains the preferred route of drug delivery inspite of various disadvantages. One such problem can be solved in the novel drug delivery system by formulating “mouth dissolving tablets” (MDTs) which disintegrates or dissolves rapidly without water within few seconds in the mouth due to the action of superdisintegrant or maximizing pore structure in the formulation. Mouth dissolving tablets are advantageous particularly for pediatric, geriatric and mentally ill patients who have difficulty in swallowing conventional tablets and capsules. The review describes the various formulation aspects, superdisintegrants employed and technologies developed for MDTs, along with various excipients, evaluation tests, marketed formulation and drugs used in this research area.
Authors and Affiliations
Alok Gupta, Anuj Mittal, K. K. Jha
Keywords
Related Articles
- EP ID EP86796
- DOI -
- Views 150
- Downloads 0
Preparation and evaluation of floating matrix tablets of Ranitidine Hydrochloride
The objective of this research was to prepare a gastroretentive drug delivery system of Ranitidine hydrochloride. Quick GI transit could result in incomplete drug release from the drug delivery system above the absorptio...
Depression - Symptoms, Causes, Medications and Therapies
Depression is the most common of the affective disorders; it may range from a very mild condition, bordering on normality, to severe (psychotic) depression accompanied by hallucinations and delusions. Worldwide, depressi...
Anti-Ulcer Activity of Sechium Edule Ethanolic Fruit Extract
Treatment with ethanolic extract of sechium edule fruit at a dose of 500mg/kg p.o significantly protected the ulceration induced by aspirin. Sechium edule fruit at a dose of 500mg/kg dody weight p.o. significantly reduce...
A Review on Osmotically Regulated Devices
Osmosis is physical phenomenon that has been extensively studied by scientist in various disciplines of science and engineering .osmotic devices are the most promising strategy based system for controlled drug delivery....
Preliminary Phytochemical Analysis of Leaf and Bark (Mixture) Extract of Ficus Infectoria Plant
Pakad (Ficus infectoria), is a large tree in Moraceae family, traditionally used in treatment of several diseases (diabetes, menstrual disorders, washing ulcers, leucorrhoea, erysipelas, epitaxis antibacterial and antifu...