Determination of Cellular Processing Rates for a Trastuzumab-Maytansinoid Antibody-Drug Conjugate (ADC) Highlights Key Parameters for ADC Design Journal title: The AAPS Journal Authors: Katie F. Maass, Chethana Kulkarni, Alison M. Betts, K. Dane Wittrup Subject(s): Medicine
Cellular Uptake Mechanism of Paclitaxel Nanocrystals Determined by Confocal Imaging and Kinetic Measurement Journal title: The AAPS Journal Authors: Yan Chen, Tonglei Li Subject(s): Medicine
Synthesis, Spectral Characterization, and In Vitro Cellular Activities of Metapristone, a Potential Cancer Metastatic Chemopreventive Agent Derived from Mifepristone (RU486) Journal title: The AAPS Journal Authors: Jichuang Wang, Jianzhong Chen, Liyuan Wan, Jingwei Shao, Yusheng Lu, Yewei Zhu, Minrui Ou, Suhong Yu... Subject(s): Medicine
Physiologically Based Pharmacokinetic Modeling to Investigate Regional Brain Distribution Kinetics in Rats Journal title: The AAPS Journal Authors: Joost Westerhout, Bart Ploeger, Jean Smeets, Meindert Danhof, Elizabeth C. M. de Lange Subject(s): Medicine
Augmentation of Therapeutic Efficacy in Drug-Resistant Tumor Models Using Ceramide Coadministration in Temporal-Controlled Polymer-Blend Nanoparticle Delivery Systems Journal title: The AAPS Journal Authors: Lilian E. van Vlerken, Zhenfeng Duan, Steven R. Little, Michael V. Seiden, Mansoor M. Amiji Subject(s): Medicine
Similar Intracellular Peptide Profile of TAP1/β2 Microglobulin Double-Knockout Mice and C57BL/6 Wild-Type Mice as Revealed by Peptidomic Analysis Journal title: The AAPS Journal Authors: Leandro M. Castro, Denise A. Berti, Lilian C. Russo, Verônica Coelho, Fábio C. Gozzo... Subject(s): Medicine
Cell Cycle Checkpoint Models for Cellular Pharmacology of Paclitaxel and Platinum Drugs Journal title: The AAPS Journal Authors: Ardith W. El-Kareh, Rachel E. Labes, Timothy W. Secomb Subject(s): Medicine
Metabolic Cleavage and Translocation Efficiency of Selected Cell Penetrating Peptides: A Comparative Study with Epithelial Cell Cultures Journal title: The AAPS Journal Authors: Christina Foerg, Kathrin M. Weller, Helene Rechsteiner, Hanne M. Nielsen, Jimena Fernández-C... Subject(s): Medicine
Cellular uptake and concentrations of tamoxifen upon administration in poly(ε-caprolactone) nanoparticles Journal title: The AAPS Journal Authors: Jugminder S. Chawla, Mansoor M. Amiji Subject(s): Medicine
Monitoring intracellular pH changes in response to osmotic stress and membrane transport activity using 5-chloromethylfluorescein Journal title: The AAPS Journal Authors: Aline Salvi, J. Mark Quillan, Wolfgang Sadée Subject(s): Medicine
Peptide delivery to the brain via adsorptive-mediated endocytosis: Advances with SynB vectors Journal title: The AAPS Journal Authors: Guillaume Drin, Christophe Rousselle, Jean-Michel Scherrmann, Anthony R Rees, Jamal Temsamani Subject(s): Medicine
The cytoplasmic escape and nuclear accumulation of endocytosed and microinjected HPMA copolymers and a basic kinetic study in hep G2 cells Journal title: The AAPS Journal Authors: Keith D. Jensen, Pavla Kopečková, John H. B. Bridge, Jindřich Kopeče... Subject(s): Medicine
A Prospective Analysis of Co-Processed Non-Ionic Surfactants in Enhancing Permeability of a Model Hydrophilic Drug Journal title: AAPS PharmSciTech Authors: Mohammed M. Alvi, Parnali Chatterjee Subject(s): Medicine
A study on the biological and immunological characteristics of Listonella anguillarum and Vibrio vulnificus extracellular products Journal title: Journal of Veterinary Medical Research Authors: F.R. El-Seedy1; W.H. Hassan1; Hala A. El-Newery2; Mona, M. Husien3 1Faculty of Veterinary Medicine... Subject(s): Veterinary Sciences
Risk Estimation of Hepatocellular Carcinoma due to Exposure to Af-latoxins in Maize from Yogyakarta, Indonesia Journal title: Journal of Food Quality and Hazards Control Authors: W.P. Rahayu, D. Herawati, W. Broto, N. Indrotristanto, S. Ambarwati, W. Adhi Subject(s): Agricultural Science, Food Science and Technology