Novel Hybrid GPU–CPU Implementation of Parallelized Monte Carlo Parametric Expectation Maximization Estimation Method for Population Pharmacokinetic Data Analysis Journal title: The AAPS Journal Authors: C. M. Ng Subject(s): Medicine
The Use of Modeling Tools to Drive Efficient Oral Product Design Journal title: The AAPS Journal Authors: Neil R. Mathias, John Crison Subject(s): Medicine
Evaluation of α2-Integrin Expression as a Biomarker for Tumor Growth Inhibition for the Investigational Integrin Inhibitor E7820 in Preclinical and Clinical Studies Journal title: The AAPS Journal Authors: Ron J. Keizer, Y. Funahashi, T. Semba, J. Wanders, J. H. Beijnen, J. H. M. Schellens, A. D. R. Huite... Subject(s): Medicine
The Use of Clinical Utility Assessments in Early Clinical Development Journal title: The AAPS Journal Authors: Anis A. Khan, Itay Perlstein, Rajesh Krishna Subject(s): Medicine
Application of a Physiologically Based Pharmacokinetic Model Informed by a Top-Down Approach for the Prediction of Pharmacokinetics in Chronic Kidney Disease Patients Journal title: The AAPS Journal Authors: Hiroyuki Sayama, Hiroaki Takubo, Hiroshi Komura, Motohiro Kogayu, Masahiro Iwaki Subject(s): Medicine
A Semi-mechanistic Model for the Effects of a Novel Glucagon Receptor Antagonist on Glucagon and the Interaction Between Glucose, Glucagon, and Insulin Applied to Adaptive Phase II Design Journal title: The AAPS Journal Authors: Joanna Z. Peng, William S. Denney, Bret J. Musser, Rong Liu, Kuenhi Tsai, Lanyan Fang, Marc L. Reitm... Subject(s): Medicine
The Utility of Modeling and Simulation Approaches to Evaluate Immunogenicity Effect on the Therapeutic Protein Pharmacokinetics Journal title: The AAPS Journal Authors: Juan Jose Perez Ruixo, Peiming Ma, Andrew T. Chow Subject(s): Medicine
Pharmacokinetics/pharmacodynamics and the stages of drug development: Role of modeling and simulation Journal title: The AAPS Journal Authors: Jenny Y. Chien, Stuart Friedrich, Michael A. Heathman, Dinesh P. de Alwis, Vikram Sinha Subject(s): Medicine
