Reduction of a Whole-Body Physiologically Based Pharmacokinetic Model to Stabilise the Bayesian Analysis of Clinical Data Journal title: The AAPS Journal Authors: Thierry Wendling, Nikolaos Tsamandouras, Swati Dumitras, Etienne Pigeolet, Kayode Ogungbenro, Leon A... Subject(s): Medicine
A Whole-Body Physiologically Based Pharmacokinetic Model of Gefitinib in Mice and Scale-Up to Humans Journal title: The AAPS Journal Authors: Youwei Bi, Jiexin Deng, Daryl J. Murry, Guohua An Subject(s): Medicine
Does the Systemic Plasma Profile Inform the Liver Profile? Analysis Using a Physiologically Based Pharmacokinetic Model and Individual Compounds Journal title: The AAPS Journal Authors: Rui Li, Tristan S. Maurer, Kevin Sweeney, Hugh A. Barton Subject(s): Medicine
Pharmacometric Models for Characterizing the Pharmacokinetics of Orally Inhaled Drugs Journal title: The AAPS Journal Authors: Jens Markus Borghardt, Benjamin Weber, Alexander Staab, Charlotte Kloft Subject(s): Medicine
Translating Human Effective Jejunal Intestinal Permeability to Surface-Dependent Intrinsic Permeability: a Pragmatic Method for a More Mechanistic Prediction of Regional Oral Drug Absorption Journal title: The AAPS Journal Authors: Andrés Olivares-Morales, Hans Lennernäs, Leon Aarons, Amin Rostami-Hodjegan Subject(s): Medicine
Comparison of Deconvolution-Based and Absorption Modeling IVIVC for Extended Release Formulations of a BCS III Drug Development Candidate Journal title: The AAPS Journal Authors: Filippos Kesisoglou, Binfeng Xia, Nancy G. B. Agrawal Subject(s): Medicine
Dose Selection Based on Physiologically Based Pharmacokinetic (PBPK) Approaches Journal title: The AAPS Journal Authors: Hannah M. Jones, Kapil Mayawala, Patrick Poulin Subject(s): Medicine
A Physiologically Based Pharmacokinetic Model of Mitoxantrone in Mice and Scale-up to Humans: a Semi-Mechanistic Model Incorporating DNA and Protein Binding Journal title: The AAPS Journal Authors: Guohua An, Marilyn E. Morris Subject(s): Medicine
Physiologically Based Pharmacokinetic Modeling to Investigate Regional Brain Distribution Kinetics in Rats Journal title: The AAPS Journal Authors: Joost Westerhout, Bart Ploeger, Jean Smeets, Meindert Danhof, Elizabeth C. M. de Lange Subject(s): Medicine
The Pharmacokinetic/Pharmacodynamic Pipeline: Translating Anticancer Drug Pharmacology to the Clinic Journal title: The AAPS Journal Authors: Qingyu Zhou, James M. Gallo Subject(s): Medicine
Physiologically Based Pharmacokinetic Model of Amphotericin B Disposition in Rats Following Administration of Deoxycholate Formulation (Fungizone®): Pooled Analysis of Published Data Journal title: The AAPS Journal Authors: Leonid Kagan, Pavel Gershkovich, Kishor M. Wasan, Donald E. Mager Subject(s): Medicine
Advanced pharmacokinetic models based on organ clearance, circulatory, and fractal concepts Journal title: The AAPS Journal Authors: K. Sandy Pang, Michael Weiss, Panos Macheras Subject(s): Medicine
Physiologically Based Absorption Modelling to Predict the Impact of Drug Properties on Pharmacokinetics of Bitopertin Journal title: The AAPS Journal Authors: Neil Parrott, Dominik Hainzl, Emmanuel Scheubel, Siegfried Krimmer, Christophe Boetsch, Elena Guerin... Subject(s): Medicine
Mechanism-Based Pharmacokinetic Modeling to Evaluate Transporter-Enzyme Interplay in Drug Interactions and Pharmacogenetics of Glyburide Journal title: The AAPS Journal Authors: Manthena V. S. Varma, Renato J. Scialis, Jian Lin, Yi-An Bi, Charles J. Rotter, Theunis C. Goosen, X... Subject(s): Medicine
Similarities and Differences in Gastrointestinal Physiology Between Neonates and Adults: a Physiologically Based Pharmacokinetic Modeling Perspective Journal title: The AAPS Journal Authors: Guo Yu, Qing-Shan Zheng, Guo-Fu Li Subject(s): Medicine
