20 Epidural Bupivacaine 0.5% and Ropivacaine 0.75% in Lower Limb Orthopedic Procedures : a comparative study
Journal Title: Indian journal of applied basic medical sciences - Year 2018, Vol 20, Issue 31
Abstract
Background Epidural blockade is one of the most useful and versatile procedures in modern anaesthesiology. Bupivacaine a long acting amide local anaesthetic though widely used but associated with side effects like neuro and cardio toxicity. Ropivacaine, developed as a possible alternative to Bupivacaine, has lower lipophilicity hence associated with a decreased potential for neuro and cardiac toxicity . [Type text] Aims Study was done to compare the haemodynamic variations , onset time and duration of sensory and motor block and complications if any of epidural anaesthesia produced by bupivacaine 0.5% and ropivacaine 0.75% in patients undergoing lower limb surgery. Methodology 60 patients, aged between 18-65 years, ASA I and II, undergoing various lower limb surgeries were randomly allocated in 2 groups of 30 each. The time for loss of pinprick at T10, intensity of motor block, duration of sensory and motor block and hemodynamic changes were assessedfor both the groups and compared . Results The time of onset and duration of sensory block was comparable for both the drugs. Bupivacaine 0.5% produced more intensity and longer duration of motor block than ropivacaine 0.75% Both the drugs were comparable with respect to hemodynamic changes. Conclusions Epidural ropivacaine 0.75% can be safely used as a possible alternative to bupivacaine 0.5% in lower limb orthopedic procedures.
Authors and Affiliations
Dr. Upasna Bhatia
Keywords
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