A Case of Anti-NMDAR Encephalitis Successfully Treated with Cyclophosphomide
Journal Title: Journal of Medical Science And clinical Research - Year 2018, Vol 6, Issue 5
Abstract
Anti-N-Methyl D-Aspartate Receptor (NMDAR) Encephalitis is a rare immune related encephalitis. The definitive diagnosis of the disease would be detection of Anti NMDAR autoantibodies in CSF fluid. The treatment are usually consist of corticosteroids, IVIG or plasma exchange. However, our patient required alternative therapy of Cyclophosphomide due to slow response to first line treatment. She was able to achieve full recovery with no relapse on 1 year follow up. We would like to share our experience of treating Anti-NMDAR Encephalitis by using Cyclophosphamide as an alternative when the first line therapy has failed. More data will be required in the future to develop an updated guideline to treat this rare disease.
Authors and Affiliations
Ka Kiat Chin
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