A Case of Metastatic Melanoma in a Female Patient with Vitiligo
Journal Title: International Journal Of Medical Science And Clinical Research Studies - Year 2023, Vol 3, Issue 2
Abstract
Patients with metastatic melanoma occasionally develop de novo hypopigmentation, pathologically indistinguishable from Sutton's nevus and common vitiligo, respectively. The case of a 68-year-old female with vitiligo of 2 years of evolution is documented, presenting a left inguinal mass and a para-aortic lymph node conglomerate. In the left inguinal region, a ganglion with thickened cortex and liquid content was identified. The laboratory results report hemoglobin of 8.30 g/dL, leukocytes 19.12 u/L, albumin 2.2 mg/dl, DHL 1222 Ul/L, alpha-fetoprotein 2 ng/ml, Ca-125 14.30 U/ml, Ca-19.9 8.60 U/ml and carcinoembryonic antigen of 2.14 ng/ml. Upon inspection, hypochromic, bilateral, and symmetrical lesions can be seen on the back of the hands, wrists, scalp, facial region, and neck. Biopsy showing malignant metastatic melanoma is performed. Starting management with Pembrolizumab 1 mg/kg every 21 days. Currently in follow-up and adjuvant treatment. Melanoma is the most aggressive form of skin cancer. The association of malignant melanoma with de novo hypopigmentation has been found, synchronously or following the diagnosis of the tumor. In recent years, it has led to the development of monoclonal antibodies. However, its diagnosis has implications for life prognosisdue to high mortality
Authors and Affiliations
Alfredo Bautista de la Cruz, Estanislao Antonio Calixto, Charit Nayelly Chang Cruz, Hamayraky Hernández González, Dora Patricia Ortega Garcia, Ana Lilia Antonio Trinidad, David Sandoval Sanchez, Jessica Ariatna Carreto Navarrete
Keywords
Related Articles
- EP ID EP739810
- DOI 10.47191/ijmscrs/v3-i2-06
- Views 47
- Downloads 0
New Approach to Brachial Plexus Block for Upper Arm Surgery
Thisstudy was conducted in western Hospital and research centre Nepalgunj from 2007 to 2010. It was a prospective non randomized study consisting 250 patient of both sex and aged between 18 and 67 years with ASA (Americ...
Small Cell Lung Cancer withMetastasis to the CentralNervous System in Secondary Care. Case Report
Neuroendocrine tumors represent approximately 20% of lung cancers; most are small cell lung cancer. The WHO classification system is used to classify lung tumors. In cases where there are clinical manifestations, these w...
Evaluation of the Efficiency of the Complex of Rehabilitation Treatment for the Outcome of the Early Period after Acute Cerebral Circulation Disorders
Based on the data of neurological examination and somatic status of 200 patients with ACVA, a plan of rehabilitation measures was drawn up for each patient. In the rehabilitation department, patients received a standard...
Implementation of Dienogest as a Treatment for Infertility in Women with Endometriosis
Abstract Fertility problems affect between 4 and 5 million couples each year in Mexico alone, according to data recorded by the National Institute of Statistics and Geography (INEGI). Endometriosis is a benign disorder...
Congestive Heart Failure for the Primary Care Physician
Congestive heart failure is a clinical condition in which the heart cannot send enough blood to meet the body's metabolic needs due to pathological cardiac changes. In recent decades, a progressive increase...