A case of pemphigus foliaceus and pustular psoriasis with a brief review of literature
Journal Title: Nasza Dermatologia Online - Year 2017, Vol 8, Issue 4
Abstract
Rarely pemphigus foliaceus could be associated with generalized pustular psoriasis. A 66-year-old woman with diffuse flaccid bullae and erosions of pemphigus foliaceus underwent two sessions of pulse therapy of corticosteroid and oral prednisolone during the interval time. Two weeks after the second session of pulse therapy with improvement of the lesions, during tapered dosage of oral prednisolone, facial annular erythematous lesions appeared and were superimposed by generalized pustular eruptions. Skin biopsy of pustular lesions showed pustular psoriasis so intramuscular methotrexate was added. Two years later, during decreasing dosage of methotrexate and prednisolone, she had eruptive recurrence of pustules and flaccid bullae associated with erythroderma and fever which were controlled with increasing dosage of corticosteroid and starting oral retinoid. These hypotheses may explain co-occurring pemphigus foliaceus and pustular psoriasis: decreasing dosage of corticosteroid, interleukin-8 overproduction in keratinocytes and increased activity of plasminogen activator in skin lesions.
Authors and Affiliations
Darjani Abbas
Keywords
Related Articles
- EP ID EP286253
- DOI 10.7241/ourd.20174.115
- Views 76
- Downloads 0
Atopic Dermatitis and Homeopathy
Introduction: Atopic dermatitis (AD) is a chronic, relapsing disorder of the skin associated with allergen sensitization and impaired barrier function. There is often a family history of pruritic skin disease or as...
Stężenie Interleukiny-1 (IL-1α, IL-1β) u chorych na łysienie plackowate
Wstęp: Łysienie plackowate to choroba charakteryzująca się ogniskowym, niebliznowaciejącym łysieniem skóry głowy lub też innych okolic ciała. Choroba ta dotyka 1-2% populacji, bez predylekcji płci ani też wieku. Et...
Topical anesthesia in cosmetic dermatological procedures
Background: Rapid increase in demand for fast, effective and painless cosmetic procedures has inspired the pursue for the ideal method of anesthesia. The aim of the study was to compare the effectiveness of different typ...
LAT, EGFR-PY197, PCNL2, CDX2, HLA-DPDQDR, bromodeoxyuridine, JAM-A, I ezryna; immunoreaktanty w spongiostycznym zapaleniu skóry
Wstęp: Ostre i podostre spongiostyczne zapalenia skóry są jednymi z najczęściej diagnozowanych rodzajów zapaleń skóry. Wielu pacjentów drapie swoje zmiany (skórne), co prowadzi do ich pogrubienia. Dokładne mechanizmy imm...
Maduromycosis of foot
-