A Challenge between Central Nervous System Infection and Lead Toxicity: Opioid Case Reports from Iran

Journal Title: Iranian Journal of Medical Sciences - Year 2019, Vol 44, Issue 2

Abstract

Although lead pollution has long been known as a cause of poisoning, it has remained a challenge to reliably diagnose it due to its common symptoms in various diseases. In this article, we report two cases of acute loss of consciousness due to the ingestion of opium-contaminated with lead. The reported cases share patterns of symptoms similar to meningitis and encephalitis which are usual etiology for the loss of consciousness. Lead poisoning is not a usual etiology for loss of consciousness and is considered in cases of occupational or environmental exposure. These reported cases showed a pattern similar to meningitis and encephalitis, but due to the unusual manifestations during their admission and coexistence with gastrointestinal symptoms, we were led to consider poisoning as the cause of consciousness loss. Lead poisoning often goes unrecognized due to a low index of suspicion, but it may turn out to be fatal. Therefore, it should be considered in the differential diagnosis of any neurobehavioral deficits in substance abusers.

Authors and Affiliations

Minoosh Shabani, Maryam Nasiri, Zohreh Aminzadeh, Hossein Hassanian Moghaddam

Keywords

Related Articles

An Epidemiological Study of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis during 2010-2015 at ShahidFaghihi Hospital,Shiraz, Iran

The Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are two ends of the spectrum of severe immunobullous state characterized by keratinocyte apoptosis. The present study aimed to draw attention to var...

Optimization of the Static Human Osteoblast/Osteoclast Co-culture System

Osteoblasts (OBs) and osteoclasts (OCs) are 2 major groups of bone cells. Their cell-to-cell interactions are important to ensure the continuity of the bone-remodeling process. Therefore, the present study was carried ou...

The Preventive Role of Pioglitazone in Glycerol-Induced Acute Kidney Injury in Rats during Two Different Treatment Periods

Background: Acute kidney injury is the most life-threatening complication of rhabdomyolysis. Glycerol is commonly used to induce this injury. The aim was to investigate the renoprotective effects of pioglitazone and the...

Induction of Apoptosis by a Combination of 2-Deoxyglucose and Metformin in Esophageal Squamous Cell Carcinoma by Targeting Cancer Cell Metabolism

Background: Both mitochondrial dysfunction and aerobic glycolysis are signs of growing aggressive cancer. If altered metabolism of cancer cell is intended, using the glycolysis inhibitor (2-deoxyglucose (2DG)) would be a...

Benign Cementoblastoma Involving Deciduous and Permanent Mandibular Molars: A Case Report

Cementoblastomas are rare benign odontogenic tumors. Diagnosis of these lesions must be made by an association of clinical, radiographic, and histopathological findings. Cementoblastomas rarely occur in both primary and...

Download PDF file
  • EP ID EP478444
  • DOI -
  • Views 83
  • Downloads 0

How To Cite

Minoosh Shabani, Maryam Nasiri, Zohreh Aminzadeh, Hossein Hassanian Moghaddam (2019). A Challenge between Central Nervous System Infection and Lead Toxicity: Opioid Case Reports from Iran. Iranian Journal of Medical Sciences, 44(2), 168-171. https://europub.co.uk./articles/-A-478444