A clinical comparative study of 0.2% levobupivacaine with 25 mcg fentanyl versus 0.2% ropivacaine with 25 mcg fentanyl for post-operative epidural analgesia in patients undergoing lower limb orthopaedic surgeries
Journal Title: Indian Journal of Clinical Anaesthesia - Year 2018, Vol 5, Issue 2
Abstract
Objectives The objectives of our study were to compare the efficacy and safety of 02 Levobupivacaine with 25 mcg Fentanyl and 02 Ropivacaine with 25 mcg Fentanyl given epidurally for postoperative analgesia in patients who were operated electively for lower limb orthopaedic conditions under spinal anaesthesiaMaterials and Methods Sixty patients belonging to American Society of Anaesthesiologists ASA Class I and II of both sexes of age within 20 60 years were included in the study after obtaining institutional ethical committee clearancePatients were divided randomly into 2 groups Group LF which received 8 ml of 02 Levobupivacaine with 25 mcg Fentanyl and Group RF which received 8 ml of 02 Ropivacaine with 25 mcg Fentanyl Surgery was conducted under spinal anaesthesia Later 8 ml of the test drug combination was given epidurally in the postoperative period when the patient complained of pain VAS score 4 and the parameters were recorded periodically until pain reappeared VAS score 4Results In both the groups mean duration of surgery changes in haemodynamics and demographic profiles were comparable However the total duration of postoperative analgesia in Levobupivacaine group was 325 6306 minutes and in Ropivacaine group was 210 2491 minutes respectively and this appeared to be statistically significantConclusion Compared to 02 Ropivacine with 25 mcg Fentanyl 02 Levobupivacaine with 25 mcg Fentanyl provides intense and longer duration of postoperative analgesia with similar haemodynamic stabilityKeywords Levobupivacaine Ropivacaine Fentanyl Postoperative analgesia Local anaesthetics
Authors and Affiliations
Sudarshan M. Boregowda, Basavanna P. Linganna, Santosh K. Raju
Keywords
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- EP ID EP476459
- DOI 10.18231/2394-4994.2018.0044
- Views 92
- Downloads 0
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