A Clinical Outcome of Dexamethasone therapy of Patients with Pyogenic Meningitis
Journal Title: Journal of Medical Science And clinical Research - Year 2016, Vol 4, Issue 7
Abstract
Objective: Observation of hastening effect of dexamethasone on recovery time and reductions of case fatality and neurological complications of pyogenic meningitis. Methodology: A total of 39 patients with pyogenic meningitis were considered on the basis of short clinical history and laboratory findings like, fever, headache, projectile vomiting, confusion/delirium, unconsciousness and neck rigidity and kerning’s sign, raised CSF pressure, presence of turbidity or purulent CSF with identification of bacteria on gram staining or culture of CSF, High CSF cell count (> 10 to < 10000 /Cumm) with neutrophilic predominance, Reduced CSF glucose level (<40mg%), Low CSF to blood glucose concentration ratio (<40 %), High CSF protein level (>50mg/dl). Results: Data was analyzed by using MS-Office software. Conclusions: Adjunctive dexamethasone therapy may improve the outcome of pyogenic meningitis in adolescent and adult patients. And the intensity of headache, vomiting and fever were also relieved by using dexamethasone therapy
Authors and Affiliations
Atul Kumar
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