A clinical study of rotaviral diarrhea in children aged 3 to 24 months
Journal Title: Medpulse International Journal of Pediatrics - Year 2019, Vol 9, Issue 3
Abstract
Background: Diarrhea is a leading cause of childhood mortality in the world accounting for 5-10 million deaths/year. In early childhood the single most important cause of severe dehydrating diarrhea is rotavirus infection. Rotavirus and other viruses causing gastroenteritis not only are major cause of paediatric mortality but also lead to significant morbidity1. The Importance of rapid diagnosis of rotavirus infection has been stressed upon to initiate prompt rehydration therapy and prevent unnecessary use of antibiotics5. In the light of above, the present study is undertaken, to study the incidence, clinical features and the association of severe dehydrating diarrhea with rotavirus infection in Cheluvamba hospital, Mysore, a tertiary care hospital attached to Mysore Medical College. Objectives of the study: 1. To study the incidence of rotavirus gastroenteritis in children b/n 3 to 24 months of age admitted to the pediatrics unit with acute diarrhea. 2. To study the clinical features of rotavirus diarrhea. 3. To study the association of severe dehydrating diarrhea with rotavirus infection. Methods: After obtaining approval from the institutional ethics committee, a descriptive and explorative study was conducted in the Department of Paediatrics in Cheluvamba Hospital, Mysore. All Paediatric patients between 3 – 24 months of age admitted with a diagnosis of acute diarrheal disease are included. Details were entered in a predesigned proforma which has detailed history, no. of episodes of loose stools, vomiting, fever. Then a detailed anthropometry, head to toe examination and systemic examination is done. Dehydration is graded as no dehydration or some dehydration and severe dehydration according to WHO criteria. Stool samples were collected from the study population, only after informed and written consent was obtained. Stool samples once collected were transported to microbiology lab as soon as possible and were tested for rotaviral antigen by ELISA test. The information was collected and data was compiled and results obtained using SPSS version 20.0 and use of Microsoft excel. Results: The incidence of rotavirus infection in all acute watery diarrhoea among children between 3 and 24 months of age is 34 %. The incidence of rotavirus infection is greater among children between 3 and 12 months (82.4%), compared to children aged 13 and 24 months (17.6%). The children with rotaviraldiarrhea, 40 (58.8%) had fever, 45(66.2%) had vomiting, 60(88.2%) had some dehydration, 8 (11.8%) had severe dehydration, 19 (27.9%) had perianal excoriation. Out of 13 cases of severe dehydration 8(61.5%) were due to rotaviral diarrhea and 5 (38.4%) were due to non-rota viral diarrhea. Though the association between rotaviral diarrhea and severe dehydration is not statistically significant, there are positive trends for severe dehydration with rotaviral diarrhea than with non-rotaviral diarrhea. Conclusion: This study revealed that the association between rotaviral diarrhea and severe dehydration is not statistically significant, there is positive association between severe dehydration with rotaviral diarrhea than with non-rotaviral diarrhea.
Authors and Affiliations
Madhurya B, Shilpasri Y M
Keywords
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- EP ID EP539262
- DOI 10.26611/1014936
- Views 178
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