A Clinico-Pathological Study of Cutaneous Lupus Erythematosus
Journal Title: Journal of Medical Science And clinical Research - Year 2017, Vol 5, Issue 11
Abstract
Background: Lupus erythematosus (LE) is a heterogenous autoimmune disease marked by diverse patterns of autoantibody production that can affect one or more vital internal organs as well as skin. Skin is the second most commonly affected organ in patients with lupus erythematosus. Skin involvement may occur alone or as a part of serious systemic disease Materials and Methods: A clinical non-interventional descriptive study was conducted in a tertiary care centre over a period of 1 year. Aim: 1. To study the clinical patterns and histopathology of these clinical patterns of cutaneous lupus erythematosus. 2. To study the risk factors, all the required data were collected by clinical examination of patients. Results: Thirty patients with clinical features of cutaneous lupus erythematosus were studied and the following observations were made. Patients with cutaneous LE ranged in age from 20-62 years. the male to female ratio was 1:5. Seventy percent of the patients were unemployed. Scaly rash was the most frequent complaint. Seventeen (56.7%) patients with cutaneous LE had systemic complaints. Majority of patients (26) had short duration illness of less than 1 year. Seventeen (56.7%) patients attributed sunlight as an exacerbating factor Chronic CLE (CCLE) was the most common form of cutaneous LE observed in this study. LE nonspecific lesions were observed in 53.3% patients with cutaneous LE. Among the 25 histopathologically diagnosed cases of classic CCLE, hyperkeratosis, follicular plugging and atrophy were present in 76%, keratotic plugging in 32%, acanthosis in 24% and hypergranulosis with parakeratosis in 4%.
Authors and Affiliations
Dr Rony Mathew
Keywords
Related Articles
- EP ID EP525443
- DOI -
- Views 77
- Downloads 0
Acute Motor and Sensory Axonal Neuropathy: A Case Report
One of the subtypes of Guillain – Barre syndrome is Acute motor and sensory axonal neuropathy (AMSAN) which is characterized by acute onset of distal weakness, loss of deep tendon reflexes, and sensory symptoms. A 65-yr-...
Role of Computed Tomography in Diagnosis of Bronchogenic Carcinoma with Histopathological Correlation
Background: In India, lung cancer is the commonest and most lethal cancer among males accounting for 10.9% of all cancer cases and 13% of cancer related mortality. Computed tomography is the modality of choice for evalua...
Takayasu Arteritis and PRES Syndrome - A Rare Case Series
PRES is a very rare manifestation of Takayasu’s arteritis. It can present with headache, seizures, altered sensorium with visual disturbances. Two young teenager patients presented in ward with complaints of severe heada...
Extra-Pulmonary Multidrug Resistant Tuberculosis (MDR-TB) Presenting As Psoas Abcess: A Rare Case Report
Introduction: MDR TB usually occurs in anti tubetubercular treatment defaulters or those with history of contact to MDR TB. But rarely it may occur as a primary case in persons without history of ATT or contact to TB pat...
Role Of Sonological Fetal Cerebellar Measurement In Gestational Age Determination
Sonographic measurement of fetal biparietal diameter is a well accepted predictor of gestational age. However there is a high variability in the calculated gestational age which increases as pregnancy progresses. The est...