A comparative study between the efficacy of 35% glycolic acid peel and triple combination cream in the treatment of melasma

Journal Title: IP Indian Journal of Clinical and Experimental Dermatology - Year 2018, Vol 4, Issue 2

Abstract

Introduction Melasma is an acquired symmetric hypermelanosis characterized by irregular light to greyish brown macules on sun exposed skin usually face It is more seen in women and is more prevalent in individuals with skin type IV V and VI The exact etiology of melasma is not known therefore various treatment modalities have been employed These include topical depigmenting agents like hydroquinone azelaic acid retinoids chemical peels low and high fluence lasers yet none have proven to being fully beneficial in our study we aim at comparing the therapeutic efficacy of 35 glycolic peel and triple combination cream in the treatment of melasmaMaterials and Methods It is a hospital based study 60 diagnosed cases of melasma were randomly enrolled equally to two groups P and Q Group P patients given serial 35 Glycolic acid peel and group Q patients given Triple combination cream to be applied topically once at night daily Followed up on 4th 8th and 12th week At each visit clinical response to treatment was calculated using MASI scoreResults At 4th 8th and 12th week post treatment evaluation Triple combination cream had an overall superiority to serial 35 glycolic acid peel as a topical hypopigmenting agentConclusion The results of the study show that Triple combination cream is a better hypopigmenting agent with rapid rate of clinical improvement when compared to 35 glycolic acid peelKeywords Melasma Triple combination cream 35 Glycolic acid peel

Authors and Affiliations

Ameen Basil, Madhavi Latha Akula, Farzana Najmuddin, Narendra J. Shetty, Monisha Shetty

Keywords

Related Articles

Early Androgenetic Alopecia and Insulin Resistance- A case control study

Background: In Androgenetic alopecia AGA, androgens induce miniaturization of hair follicles in those genetically predisposed to baldness. The previously known association between Androgenetic Alopecia AGA and cardiovasc...

Vitiligo following intravitreal ranibizumab: An association or an unrelated event?

Age-related macular degeneration (ARMD) is the most common cause for visual impairment in the elderly in western countries. Its incidence in India is expected to increase with the increase in the size of geriatric popula...

Role of venereal disease in increased risk of erectile dysfunction in men attending a tertiary health centre in south India

Erectile dysfunction(ED) is a major cause of concern among men. Sexual health is as important as physical health as it has a significant effect on the quality of life both in the patient and his spouse. Men with a previo...

Fixed drug eruption to cetirizine – role of patch testing

Antihistamines are prescribed for a wide variety of disorders like urticaria, eczema, allergies and infestations. Adverse reactions due to them is unusual and the incidence of fixed drug eruption is scarce. They are char...

Impact of psoriasis on serum lipid profile, CRP, ADA: A controlled study of 25 patients

Introduction Psoriasis is a chronic disorder with certain systemic compounds It has been associated with increase in morbidity and mortality from cardiovascular events especially in chronic casesAims and Objectives To co...

Download PDF file
  • EP ID EP488877
  • DOI 10.18231/2581-4729.2018.0029
  • Views 93
  • Downloads 0

How To Cite

Ameen Basil, Madhavi Latha Akula, Farzana Najmuddin, Narendra J. Shetty, Monisha Shetty (2018). A comparative study between the efficacy of 35% glycolic acid peel and triple combination cream in the treatment of melasma. IP Indian Journal of Clinical and Experimental Dermatology, 4(2), 123-131. https://europub.co.uk./articles/-A-488877