A comparative study in cataract patients of south India undergoing manual small incision cataract surgery between topical dexamethasone 0.1% and topical nepafenac 0.1% ophthalmic solutions
Journal Title: Medpulse International Journal of Ophthalmology - Year 2018, Vol 7, Issue 2
Abstract
Aim: To study the effect of topical dexamethasone 0.1% and topical nepafenac 0.1% ophthalmic solutions in cataract patients, undergoing manual small incision cataract surgery. Method: The effect of nepafenac 0.1% following cataract surgery was studied and compared to routine corticosteroid, dexamethasone 0.1% in a randomized prospective clinical trial. Both groups were similar in baseline parameters. Postoperative inflammatory response, intraocular pressure, corneal thickness following manual small incision cataract extraction were assessed in both groups in the initial 8 weeks and the severity of these were graded at 1, 2, 7, 28 and 56 days. Intraocular pressure, anterior chamber reaction, corneal thickness at baseline and endpoint were compared and statistically analyzed. Results: The two groups did not differ much in treatment effect for any of the variables. However there seemed to be a little increase in IOP and not very significant reduction in corneal thickness with dexamethasone. Conclusion: Topical nepafenac is as effective as topical dexamethasone and can be used as an alternative in routine postoperative treatment following cataract surgery
Authors and Affiliations
R Santhanalakshmi, S Karthick
Keywords
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- EP ID EP413309
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