A COMPARATIVE STUDY OF ATTENUATION OF STRESS RESPONSE DURING INTUBATION WITH ESMOLOL AND PROPOFOL
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2018, Vol 5, Issue 2
Abstract
BACKGROUND Endotracheal intubation for giving anaesthesia and for other purposes have become integral part of anaesthesiology. Tracheal intubation provides a patent airway for unconscious person. For endotracheal intubation, direct laryngoscopy is a tool. Direct laryngoscopy and passage of endotracheal tube are noxious stimuli that can provoke adverse responses in cardiovascular system. To prevent adverse responses different drugs are used in different methods. In the present study, we are comparing the effects of esmolol and propofol to obtund adverse responses in the cardiovascular system. MATERIALS AND METHODS Hospital-based prospective randomised comparative study, which includes 70 normotensive patients aged 15 to 60 years of either sex belonging to ASA I and II, Mallampati class 1 and 2 posted for various elective non-cardiac surgeries. In this study, the group 1 patients received esmolol 1 mg/kg bolus and in group 2 propofol 1 mg/kg bolus after 1 minute of induction. Haemodynamic parameters were recorded (SBP, DBP, MAP and HR) before and after intubation and compared. RESULTS The mean heart rate in both group 1 and 2 reduced significantly from preoperative value after 2 minutes of drug administration. The mean values of the haemodynamic parameters HR, SBP, DBP and MAP were compared in group 1 and 2 after 5 minutes of intubation. There is no statistically significance between the two groups as the p value >0.05. CONCLUSION Both esmolol and propofol were effective in attenuation of haemodynamic response to laryngoscopy and intubation.
Authors and Affiliations
Vallem Balasubramanyam, Sowmya G, Sai Suraj K. N, Talisetti Jamuna
Keywords
Related Articles
- EP ID EP448614
- DOI 10.18410/jebmh/2018/33
- Views 79
- Downloads 0
A STUDY OF PLEURO-PULMONARY MANIFESTATIONS IN SYSTEMIC SCLEROSIS - HOSPITAL BASED OBSERVATIONAL STUDY
BACKGROUND Systemic sclerosis (SSC) is a chronic multisystem disorder of unknown aetiology characterized clinically by thickening of the skin caused by accumulation of connective tissue and by involvement of visceral org...
HOSPITALIZATIONS DUE TO RESPIRATORY PROBLEMS DURING DIWALI FESTIVAL IN A TERTIARY CARE HOSPITAL IN SOUTH INDIA
BACKGROUND The burning of firecrackers during Diwali festival produces an adverse respiratory outcome. However, there are no published articles on the impact of fireworks on hospital admission due to acute respiratory is...
STUDY AND OUTCOME OF MECHANICALLY-VENTILATED PAEDIATRIC PATIENTS IN INTENSIVE CARE SETUP IN TERTIARY CARE HOSPITAL
BACKGROUND Mechanical ventilation is one of the modality of treatment in critically ill children and can be lifesaving in many cases if done with meticulous care. It is associated with complications, which adversely infl...
SEARCH TO FIND OUT CAUSE OF COMPLICATIONS OF DIABETIC PATIENT WHO WENT ON VENTILATOR AFTER OPEN CHOLECYSTECTOMY
Diabetes is very common now-a-days. Incidences of diabetes are increasing day by day. If not managed properly it is a slow killing disease. Its detrimental effects on various organs are not revealed clinically during ini...
POST-OPERATIVE MORTALITY IN INTERTROCHANTERIC FRACTURES IN ELDERLY
BACKGROUND Mortality after surgical treatment of hip fracture at the end of one-year ranges from 5- 50% according to western literature. Very few studies on this issue have been done in India. This study aims to answer t...