A comparative study of Dexmedetomidine and Clonidine as an adjuvants to 0.5% Ropivacaine in upper limb surgeries done under Supraclavicular brachialplexus block
Journal Title: Medpulse International Journal of Anesthesiology - Year 2018, Vol 6, Issue 2
Abstract
Background: Regional anaesthetic techniques are highly effective in allevating pain during various surgical procedures. The role of peripheral nerve block has expanded from the operating room into the arena of postoperative and chronic pain management. Addition of adjuvants decreases the dose of local anaesthetics and thereby decrease the potential local anaesthetic toxicity. The objective of our study was to compare the clinical profile of Alpha two agonists Dexmedetomidine and Clonidine as an adjuvant to Ropivacaine in supraclavicular brachial plexus block with respect to sensory and motor blockade, level of sedation and duration of analgesia.. Material and Methods: Sixty adult patients of ASA Grade I and II posted for elective upper limb surgeries under Supraclavicular brachial plexus block were randomly divided into 2 groups. Group C: 29 ml of 0.5 % Ropivacaine with Clonidine 1 mcg/kg ( volume 30 ml). Group D: 29 ml of 0.5 % Ropivacaine with Dexmedetomidine 1 mcg/kg( volume 30 ml).assessment of sensory blockade was done by Hollmen scale whereas motor block assessment was done by Bromage Scale. Degree of pain was evaluated by Visual Analogue Scale. Level of sedation was assessed by 5 point sedation scale. Results: There was statistically significant difference between the groups for onset of sensory and motor blockade, time for complete sensory and motor block, total duration of sensory and motor blockade as well as for duration of analgesia. Sedation scale score and Visual Analogue Scale score except at 6 Hrs were comparable between the groups. Conclusion: Dexmedetomidine is a better adjuvant to Ropivacaine for supraclavicular brachial plexus block when compared to Clonidine as it provides earlier onset of sensory and motor blockade, prolongs the duration of blockade and postoperative analgesia withminimal side effects.
Authors and Affiliations
Sonali M Khobragade, Balkrishna Bagwale, Sandhya Manjrekar
Keywords
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