A comparative study of efficacy and safety of 5% topical minoxidil with platelet rich plasma versus platelet rich plasma as a monotherapy in male patients with androgenetic alopecia
Journal Title: IP Indian Journal of Clinical and Experimental Dermatology - Year 2018, Vol 4, Issue 3
Abstract
Introduction Male baldness is genetically determined most common gradually progressive hair disorder leading to miniaturization of hair follicles Various modalities have been used in various studies without significant resultsObjective The aim was to study and compare the two modalities of treatment and to evaluate their resultsMaterials and Methods This is prospective comparative study Sample size was 40 twenty in each group Group 1 was given 5 topical minoxidil solution two times in a day till six months and platelet rich plasma PRP Group 2 was given only PRP at three weekly interval for six months Parameters evaluated before starting after three months and after six months for Hair pull test anagentelogen ratio Patients Physicians assessment and clinical photographsResults On evaluating group 1 showed relatively more significant improvement On hair pull test significant reduction of hair breakage in group 1 Anagentelogen ratio showed 89 03 improvement in anagen hair in group 1 while 59 05 was in group 2 Improvement was seen in patients of group 1 more than patients of group 2 based on patients assessment and photographsConclusion 5 minoxidil when given with platelet rich plasma was superior and better when compared to platelet rich plasma aloneKeywords AGA PRP Minoxidil
Authors and Affiliations
Prashanth R. Kamath, Saumya Goel, Ashok Menon, Amita Murali Babu, Hafsa Eram
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