A COMPARATIVE STUDY OF INTRAVENOUS IRON SUCROSE WITH ORAL IRON FERROUS SULPHATE IN TREATMENT OF ANAEMIA IN ANTENATAL MOTHER
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2018, Vol 5, Issue 32
Abstract
BACKGROUND Anaemia is the most common medical disorder in pregnancy. Iron Sucrose is a suitable alternative source of iron which is well tolerated with few mild side effects to combat this massive problem of anaemia. The aim of the study was to compare the efficacy of intravenous iron sucrose with oral iron ferrous sulphate for treatment of anaemia in pregnancy. MATERIALS AND METHODS It is an open-label parallel group hospital based randomized controlled trial to evaluate the efficacy and safety of Parenteral iron with oral iron for treatment of anaemia in antenatal mother attending Agartala Govt. Medical College at antenatal clinic. 50 subjects in each group were included. Independent t test and chi square test was applied. RESULTS The present study showed statistically significant rise in haemoglobin (Hb%) in IV Iron sucrose compared to oral iron. The rise of Hb% is 3.19 gm% in IV Iron sucrose in comparison to 2.44 gm% in oral iron group within a span of 4 weeks. There was no major side effect in IV group as compared to mild to moderate side effects in about 36% subjects in oral iron group. CONCLUSION The study reveals that intravenous iron sucrose therapy was better tolerated with higher increase in mean Hb% and packed cell volume (PCV) when compared with oral iron therapy.
Authors and Affiliations
Salilbindu Chakraborti, Amullya Debbarma, Jayanta Ray
Keywords
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- EP ID EP570966
- DOI 10.18410/jebmh/2018/486
- Views 85
- Downloads 0
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