A Comparative Study of Lipid Profile in HIV Infected and non Infected Subjects at a Tertiary Care Centre
Journal Title: Journal of Medical Science And clinical Research - Year 2017, Vol 5, Issue 11
Abstract
Introduction: Metabolic derangements and body fat abnormalities are well known in HIV infection, both due to virus and to treatment. Various abnormalities in lipids are described in HIV. Increased triglyceride, low total cholesterol, low HDL, low LDL have been noted prior to treatment. With better medication and care, longevity of patients has increased resuting in worsening cardiovascular morbidity. It is hence mandatory to document the pretreatment lipid profile in HIV infected patients. Materials & Methods: A comparative cross sectional study of 50 treatment naïve HIV infected patients and 50 non infected controls were included in the study. Subjects were those attending the ART clinic, and HIV positivity was confirmed by NACO guidelines. Informed consent and ethical clearance and permission from KSACS were obtained. Patients with comorbidities likely to influence the lipid profile were excluded from the study. Detailed history, clinical examination data including anthropometry were entered in proforma. Lipid profile was tested in both groups. Results were computed and analysed using SPSS software. Results: There were significant differences in lipid profile between HIV infected and non infected groups. There was statistically significant lowering of total cholesterol LDL, HDL and elevation of triglycerides & VLDL in HIV infected. There was proportionate reduction in total cholesterol, LDL and HDL as CD4 count decreased. TG, VLDL increased as CD4 decreased. ( P <0.05). Conclusions: Pretreatment lipid abnormalities in lipid profile noted were lower TC, HDL & LDL and higher TG& VLDL. The abnormalities linearly correlated with CD4 counts.
Authors and Affiliations
Dr Radha . T. R
Keywords
Related Articles
- EP ID EP523780
- DOI -
- Views 99
- Downloads 0
Clinico-Epidemiological Profile of Myiasis Patients Attending a Tertiary Care Hospital of Jharkhand: A Retrospective Study
Introduction: Infestation of the natural orifices and body tissues by the larvae of flies is a complaint commonly encountered by several patients presenting in Ear, Nose, Throat and Head and Neck Surgery (ENT & HNS) OPD...
A Delta Beta Thalessemia Female with Autoimmune Hemolytic Anemia due to Epstein Barr Virus: A Case Report
A number of extrinsic agents and disorders may lead to premature destruction of red blood cells. Among the most clearly defined are antibodies associated with immune hemolytic anemias.(1) The hallmark of this group of di...
A Comprehensive Study of 100 Patients of SSI (Surgical Site Infections) in Patients Undergoing Abdominal Surgery, Elective/Emergency, in Our Hospital
Background: Surgical site infections (SSIs) are any infections occurring in a surgical wound within 30 days. SSIs are real risks associated with significant burden in terms of patient morbidity and mortality, and costs t...
Comparative Analysis on the Functional Outcome Following Internal Fixation of Midshaft Clavicle Fractures with Plate against Titanium Elastic Nail
Introduction: Injuries around the shoulder resulting in clavicle fractures accounts for about 5% to 10% of all the fractures. When we consider the shoulder girdle injuries alone, clavicle fractures accounts for about 50%...
Etiology of Primary Dislocation in Recurrent Anterior Shoulder Instability: A Cross-Sectional Study
Introduction: Shoulder joint is the most unstable and frequently dislocating joint because of its anatomy and biomechanics. In most patients shoulder instability occurs after a clear traumatic insult. According to one es...