A comparative study of serum electrolytes in newborns with birth asphyxia and non-asphyxiated newborns
Journal Title: Pediatric Review: International Journal of Pediatric Research - Year 2018, Vol 5, Issue 8
Abstract
Background: Birth asphyxia is a common neonatal problem and contributes significantly to neonatal morbidity and mortality. HIE is the foremost concern in asphyxiated neonate because contrary to other system derangements this has the potential to cause serious long term neuromotor sequel among survivors. Sodium, potassium and calcium are the major electrolytes in human body, and any deviation from their normal levels in blood might cause convulsions, shock and other metabolic abnormalities. Immediate aggressive treatment of these abnormalities could modify the entire outcome of the babies. Methods: The study was a case control study conducted over a period of 2 years. Case (asphyxiated) group comprised of term babies weighing 2.5 kg or more with birth asphyxia. Birth asphyxia was said to be present in those babies who had a definite APGAR score of less than 7 at 1 minute of birth. Control (non-asphyxiated) group was made up of term babies weighing 2.5 kg or more with APGAR scores of 7 or more at 1 minute of birth. Blood samples collected were immediately sent to the biochemistry lab for evaluation of serum sodium, potassium and calcium. Results: A total of 100 newborn babies were included in the study, 50 babies in case group and 50 babies in control group. Mean serum sodium and calcium values were significantly lower in the asphyxiated group when compared to the non-asphyxiated group. Mean serum potassium was significantly higher in the asphyxiated group when compared to the non-asphyxiated group. The mean serum sodium and calcium values in severely asphyxiated babies were significantly lower when compared to mild/moderately asphyxiated babies and the non-asphyxiated group. Conclusions: As serum sodium levels are low in birth asphyxia, fluids must be managed judiciously in asphyxiated newborns.
Authors and Affiliations
Manjunatha Babu R, Pavan Kumar Jerry, Harish G, Susheela C
Keywords
Related Articles
- EP ID EP408695
- DOI 10.17511/ijpr.2018.8.05
- Views 137
- Downloads 0
Atypical Presentation of Celiac Disease: A Case Report
Celiac disease is a chronic inflammatory immune-mediated condition associated with small intestinal injury triggered by gluten present in wheat, barley and rye, leading to malabsorption of different nutrients. Usually it...
Study of features associated with death in children with severe malaria at a tertiary care hospital in Western India
Background: India contributes significantly to world malaria load and it accounts for 6% of the total malaria cases, 49 % of the vivax malaria cases and 51% of vivax malaria deaths across the world. There is scarce infor...
The role of structured handouts in improving the teaching learning process of final year MBBS students
Introduction: Teaching includes application of various teaching learning methods by a teacher to transfer knowledge and skills to a student. It requires a lot of effort and talents to modify the method more effectively,...
Prevalence of anemia and its etiology: a study in a semi urban area
Introduction: Anemia is recognized as a public health problem throughout the world affecting both developed and developing countries and is associated with nutritional deficiencies especially due to iron deficiency, whic...
Profile of Anemia with special reference to hemoglobinopathies in a tertiary care centre in Madhya Pradesh
Introduction: Haemoglobinopathies constitute very important causative factors for anemia of childhood, especially in those regions where abnormal hemoglobin genes are highly prevalent. Thalassemia and Sickle cell anemia...