A COMPARATIVE STUDY OF SERUM IRON AND FERRITIN BETWEEN PRE-TREATED BREAST CANCER PATIENTS WITH HEALTHY CONTROLS OF THE SAME AGE GROUP
Journal Title: Journal of Advanced Medical and Dental Sciences Research - Year 2017, Vol 5, Issue 11
Abstract
Introduction: Breast cancer is one of the leading cause of cancer related deaths in women and there are differences in breast cancer recurrence, aggressiveness and incidence between premenopausal and postmenopausal women.Materials & Methods: The study was conducted in the Department of Biochemistry in collaboration with Department of Surgery and Radiotherapy, G.G.S. Medical College Faridkot. Serum Iron & Ferritin levels were compared in the premenopausal and postmenopausal breast cancer women with the age and sex matched healthy controls of the same age group. All the patients included were pretreated and had not undergone any Surgery, Chemotherapy, Radiotherapy and Hormone therapy.Results: Iron and ferritin levels were found to be lower in premenopausal women than controls (p<0.05 and p<0.05). But in postmenopausal women iron and ferritin levels were found to be higher in postmenopausal women as compared to controls(p=0.14 and p<0.05).Conclusions:Iron is a double edge sword as both low and high levels of iron can cause the increased risk of breast cancer.
Authors and Affiliations
K. M. D. S Panag, D. S Sidhu, Gitanjali Goyal, Raja P. S Banipal, Jasmeet Singh
Keywords
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