A Comparative Study of Spot Urine Protein Creatinine Ratio With 24 Hours Urine Protein Excretion For Estimation Of Proteinuria In Preeclampsia.
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 10
Abstract
Objective: To determine the correlation between single voided sample (spot urine PCR) and 24 hours urine protein excretion in patients being evaluated for preeclampsia. This study was conducted in Niloufer hospital and sample size is 100. Methods: A random urine sample was collected after discarding the first morning specimen. A single voided urine specimen was obtained soon after the 24 hour urine collection, before midday. Urine protein was performed on semi automated analyser. Urine creatinine was measured by the Jaffes reaction. The protein creatinine ratio was calculated by dividing the urinary protein concentration by the urinary creatinine concentration and the correlation with the 24 hours urine protein was assessed. Results: A fair correlation coefficient of r=0.902 was observed between the 24 hour urine protein and spot urine protein creatinine ratio among 100 subjects which was statistically significant at P value <0.001. Conclusion: There is strong correlation between spot pcr and 24 hour urine protein estimation. The present study indicate that this method for quantification of proteinuria can provide valuable information.Its is a satisfactory substitute for the determination of protein excretion in 24 hours collection.
Authors and Affiliations
Dr. Y. INDIRAMANI, Dr. K. ARUNA KUMARI
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