A comparative study of successful abortion rate of mifepristone –misoprostol combination versus extra amniotic ethacridine lactate – misoprostol for termination of second trimester pregnancy at tertiary health care center
Journal Title: Medpulse International Journal of Gynaecology - Year 2019, Vol 9, Issue 2
Abstract
Background: Mid-trimester abortion constitutes 10–15% of all induced abortions but is responsible for two-thirds of all major complications. There is a gradual increase in second trimester abortions because of the wide-scale introduction of prenatal screening programs detecting women whose pregnancies are complicated by serious fetal abnormalities. Aims and Objectives: To study successful abortion rate of mifepristone –Misoprostol combination versus exrtaamniotic ethacridine lactate–misoprostol for termination of second trimester pregnancy at tertiary health care center. Methodology: This was a cross-sectional study carried out in the department of OBGY during the one-year period i.e. January 2017 to January 2018 in the patients who needed medical termination of pregnancy in the second trimester of pregnancy. During the one year period there were 60 patients with written explained consent were given exrtaamniotic ethacridine (Group E) mifepristone –Misoprostol (Group M) randomly. Abortion interval (Hrs.) and Outcome etc. were noted. The statistical analysis was done by chi-square test and calculated by SPSS 19 version software. Result: In our study we have seen that the Abortion interval (Hrs.)- <12 were 6.67% and 26.67%; 12-18 were 43.33% and 66.67%; 18-24 were 50.00% and 6.67% respectively in Group M and Group E . The complete Outcome of Abortion 80.00% and 90.00% ; Incomplete was 20.00% and 10.00% respectively in Group M and Group E this was comparable with each other (X2=1.17, df=1, p<0.27). Conclusion: It can be concluded from our study that mifepristone –Misoprostol was superior to exrtaamniotic ethacridine lactate – misoprostol with respect to less induction to Abortion interval but the outcome in terms of success full abortion was comparable in both of them.
Authors and Affiliations
Kanjula Sirisha Mahi
Keywords
Related Articles
- EP ID EP470793
- DOI 10.26611/1012929
- Views 137
- Downloads 0
Maternal outcome in eclampsia in MKCG medical college and hospital, Berhampur, Odisha
Objective: Hypertensive disorders complicate 5-10% of all pregnancies globally¹& 10.08% in India. Eclampsia is an obstetric enigma and a major cause of serious maternal morbidity and maternal mortality. Majority of the d...
A study of clinical profile and factor associated with PIH at tertiary health care centre
Background: Pre-eclampsia is pregnancy-induced hypertension (PIH) of unknown etiology. Pre-eclampsia can be quite serious as it can lead to various complications both for the mother and the baby. Aims and Objectives: To...
Evaluation of maternal and perinatal morbidity and mortality in previous caesarean section cases
Background: According to World Health Organization “There is a story behind every maternal death and life-threatening complication. Aims and Objectives: To Evaluate maternal and perinatal morbidity and mortality in previ...
Placental changes in patients of asthma and tuberculosis with relation to fetal outcome
Background: The potential benefits of placental examination include clarification of pathological features, improved management of subsequent pregnancies. Aim: To study the placental changes in patients of asthma and tub...
Study of antenatal and intrapartum risk factors associated with meconium stained amniotic fluid
Background: Meconium aspiration syndrome (MAS) is an important cause of morbidity and mortality among newborns in the developing world. Meconium stained infants are considered 100 times more likely to develop MAS, compar...