A Comparative Study of the Toxicities and Local Recurrence of Conventional External Beam Radiotherapy versus Hypofractionated Radiotherapy in Breast Cancer Patients
Journal Title: International Journal of Current Science Research and Review - Year 2023, Vol 6, Issue 12
Abstract
Introduction: Breast cancer is the most common cancer amongst women, which is treated by a multi-modality approach consisting of surgery, chemotherapy, radiotherapy, hormonal therapy, targeted therapy and immunotherapy. Objective: The aim of the study is to compare the early and late treatment toxicities and the local recurrence following Conventional and Hypofractionated External Beam Radiotherapy in breast cancer patients after surgery. Methods: A randomized study was conducted for two years including 150 patients. The patients were divided into two arms, with Arm-A receiving a total dose of 50Gy/25# and the Arm-B receiving 40Gy/16#. Results: Early and late treatment toxicities were comparable in both the arms, except for skin toxicity which was more in the hypofractionated arm (Arm-B). Local Recurrence was observed in Arm-A in 1 patient at Month 17 of follow-up, and in Arm-B at Month 13 in 1 patient and at Month 21 in 1 patient. Conclusion: Hypofractionated radiotherapy given over a short period of time is comparable to Conventional fractionation radiotherapy without any significant statistical difference in terms of toxicities or local recurrence; with an added advantage of reduced treatment time, reduced duration of hospital stays, better patients’ compliance and reduced cost of treatment.
Authors and Affiliations
Silchang Koknal Marak, Rahul Mahawar, Ningthoujam Dinita Devi, Nongmaithem Nilima Devi, Yumkhaibam Sobita Devi, Kishalay Baidya,
Keywords
Related Articles
- EP ID EP725279
- DOI 10.47191/ijcsrr/V6-i12-48
- Views 43
- Downloads 0
Solar Wind Plasma Parameters in Relation with Good Quality Magnetic Cloud Related Geomagnetic Storms
We have analyzed magnetic cloud related geomagnetic storms detected during the period of solar cycle 23 and 24 with disturbances in solar wind plasma parameters. We have observed that all the MC related geomagnetic storm...
Outpatient Length of Stay (OLOS) Analysis at Edelweis Hospital using Machine Learning Algorithm
Patient satisfaction may be impacted by the length of stay (LOS) that a patient perceives during an outpatient clinic visit. With the increasing competition in the healthcare industry and patients’ demands for higher-qua...
The Dual Dance: Strategies for Success in Profit and Cash Flow Management
This comprehensive guide delves into the intricate dynamics of managing profit and cash flow, offering financial managers a strategic roadmap for achieving a delicate balance. Beginning with an exploration of the symbiot...
Mood States (POMS) Condition Profile Analysis of Senior Women's Cricket Athletes in East Java before The North Aceh Sumatra PON 2024
One factor that could affect an athlete’s mental and emotional readiness is mood. Mood profile for Cricket athletes is an important factor that needs to be analyzed. An athlete’s mood can affect their overall performance...
Design of Knowledge Flow According to the Approach of Self-Regulation Learning for Teaching Maths on Chatbot
Each student has different skills, interests, and learning paces in a classroom. If each student has a personal tutor to support learning according to their ability, it will improve the quality of teaching and no student...