A comparative study on rectal misoprostol versus intramuscular oxytocin to prevent postpartum haemorrhage

Journal Title: The New Indian Journal of OBGYN - Year 2016, Vol 2, Issue 2

Abstract

Objective: To see the efficacy of rectal misoprostol in comparison to intramuscular oxytocin in prevention of postpartum haemorrhage in low risk patient. Methodology: A prospective, double-blind study carried out for a period of 1 year. 400 cases had been taken for the study, which were divided randomly into two groups containing 200 cases each. ie. Group A (600 µgm misoprostol rectally given immediately following delivery of baby) and Group B (10 IU of oxytocin given intramuscularly immediately after delivery). The personal information and medical data of the selected cases were collected in structured proforma. Statistical analysis was done using SPSS version 15.0. Results: The mean third stage blood loss was 185±84.42 ml and 168±68.38ml in misoprostol group and oxytocin group respectively with significant difference (p<0.05). Mean change in Hb% (gm/dl) pre and post delivery was 0.89±0.32SD (gm/dl) in misoprostol group and 0.83±0.28SD (gm/dl) in oxytocin group (p>0.05). Incidence of PPH was 3% and 2% in group A and group B respectively (p>0.05). Shivering, pyrexia was found more in misoprostol group than oxytocin with the incidence being 20.5% versus 2% (shivering) and 8.5% versus 0.5% (pyrexia) respectively. Conclusion: It is observed that the misoprostol 600µg rectally is less effective than intramuscular oxytocin 10 IU when used as prophylactic uterotonic during the active management of third stage of labour.

Authors and Affiliations

Bijoy Kumar Dutta, Komal Rani Gupta

Keywords

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  • EP ID EP451314
  • DOI 10.21276/obgyn.2016.2.2.7
  • Views 127
  • Downloads 0

How To Cite

Bijoy Kumar Dutta, Komal Rani Gupta (2016). A comparative study on rectal misoprostol versus intramuscular oxytocin to prevent postpartum haemorrhage. The New Indian Journal of OBGYN, 2(2), 98-103. https://europub.co.uk./articles/-A-451314