A comparative study on the antioxidant properties of curcuminoids and its rubrocurcumin analogues
Journal Title: Bulletin of Pure and Applied Sciences Sec. C – Chemistry - Year 2018, Vol 37, Issue 1
Abstract
The yellow colored pigment, curcumin present in turmeric is responsible for its various biological activities like antioxidant, anti-inflammatory and anticarcinogenic activity. Different functional group present in curcumin includes a β–diketone group, carbon–carbon double bond and two phenyl rings with hydroxy and methoxy substituents. A controversy exists in literature on the site and mechanism for the antioxidant activity (AOA), the keto–enol/phenolic moiety present in curcumin. In the present work AOA of curcuminoids and its boron complex with oxalic acid – rubrocurcumin analogues were conducted which differ in the substituent in the benzene ring. Since in rubrocurcumin analogue β-diketone group is blocked through bonding with boron its influence will be absent in its antioxidant activity.
Authors and Affiliations
Balachandran S
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