A Comparative Study to Assess the Effectiveness of using Air, a 50% N2 O:O2 and Lignocaine 2% to Inflate the Endotracheal Tube Cuff During General Anaesthesia
Journal Title: International Journal of Contemporary Medical Research - Year 2017, Vol 4, Issue 3
Abstract
Introduction: Endotracheal tube (ETT) is one of the most frequently used mode for administering general anesthesia at the time of surgeries and it provides an artificial channel through which the inhalational anesthetic agents like halothane, isoflurane, sevoflurane, nitrous oxide(N2 O) can be delivered to the lungs. An ETT cuff when inflated with either Air, N2 O, saline, lignocaine during general anaesthesia will have complications like emergence phenomenon and post-operative sore throat. Study objectives were to find out the most effective intra-cuff inflating agent among air, a 50% gaseous mixture of N2 O: O2 and 2% lignocaine and to assess post-operative sore throat pain in each group. Material and methods: The present study was a comparative study carried out in adult patients who underwent surgeries under general anaesthesia during Oct 2014-May16. Study was done in KMC Attavar hospital and KMC hospital Jyothi circle, Mangalore and District government Wenlock hospital, Mangalore. For comparison of cuff pressures, with an α error of 5%, β error of 20% and mean difference in pressure of 10cm H2 0 and variance of 15cmH2 0, the sample size was 105 with 35 subjects in each armGroup A (Air), Group N (N2 O: O2 ) and Group L (lignocaine). Randomization of the subjects into study groups was done after obtaining a written informed consent and the study has been approved by Institutional Ethics committee. Results: Out of 105 study subjects, 59(56.2%) were found to be male and 46(43.8%) were found to be female. Mean age of the participants was 39.4±10.8 years. ANOVA test showed a significant difference in mean cuff pressures in three groups with air showing an increased cuff pressures, Group N showed decreased and L with stable pressures (p<0.001). Conclusion: The use of lignocaine 2% to inflate the endotracheal tube cuff provides stable intracuff pressure and reduces the incidence of sore throat pain when compared to air and a mixture of 50% N2 O:O2 .
Authors and Affiliations
Puneeth Nagarajaiah, Jesni Joseph Manissery, Thrivikram Shenoy, Usha Rani S Padmanabha
Keywords
Related Articles
- EP ID EP426490
- DOI -
- Views 111
- Downloads 0
Bowen’s Disease in Kashmir - A Pilot Study
Introduction: Bowen’s disease (BD) is an in situ squamous cell carcinoma (SCC) which was first described in 1912 by JT Bowen. Clinically a typical BD is a slowly enlarging erythematous patch or plaque which is well demar...
Salivary Glucose Level and its Correlation With Blood Glucose Level in Patients with Diabetes Mellitus-an in-Vivo Study
Introduction: Diabetes mellitus is a globally widespread metabolic disease caused due to hyperglycemia, which is the result of defect in insulin secretion, insulin action, or both. The aim of the study was to assess the...
Spectrum of Opportunistic Infections in HIV Seropositive Patients at ART Centre, PGIMS, Rohtak
Introduction: HIV infection leads to AIDS and opportunistic infections are the major cause of morbidity and mortality in such patients, which considerably affect the health and quality of life of people infected with HIV...
Study of Lipid Profile and Glycated Haemoglobin Level in Type 2 Diabetic Complications
Introduction: For predicting complications of Diabetes Mellitus (DM), HbA1c concentration is the most important risk factor. Maintaining HbA1c level below 6.5% is critical to decrease the incidence of diabetic complicati...
Risk Factors for Stress Urinary Incontinence in Women
Urinary incontinence incurs serious medical, social, psychological, and economical implications, adversely affecting quality of life. Many women with SUI do not seek care for their condition as they are embarrassed to sp...