A comparative study to know the effectiveness of butorphanol versus fentanyl in laparoscopic surgeries for balanced anaesthesia
Journal Title: Medpulse International Journal of Anesthesiology - Year 2019, Vol 10, Issue 3
Abstract
Background:Fentanyl and butorphanol both opioids are belonging to different subgroupsare in usefor balanced anaesthesia for long time.The present study aimed to compare effectiveness ofbutorphanolvs fentanyl in laparoscopic surgeries for balanced general anaesthesia.Material and Methodology:The present study is randomised comparative study. Total 70patients of ASA grade I and II, aged between 20-50 years, of both sex were selected from routine operative list after taking written consent and were divided into 2 groups, each of 35.Group B:Inj Butorphanol 1mg just after induction, repeated with 0.5mg after 30 mins. Group F:Inj Fentanyl 2µg/kg just after induction repeated with 0.5µg/kg after 30 mins.Induction was done with Inj Propofol 2mg/kg and Inj Succinylcholine 1.5 mg/kg iv. Intubation was done with oral cuffed portex endotracheal tube and anaesthesia was maintained with 33% O2 and 66%N2O, traces of isoflurane, Inj vecuronium as a muscle relaxant and intermittent positive pressure ventilation. Intraperitoneal gas insufflation of CO2 was allowed upto Intraabdominal pressure between 14 to 15 mmHg.At the end of the surgery patients were reversed with Inj Neostigmine 0.06 mg/kg and Inj Glycopyrrolate 8 µg/kg intravenously.Mean arterial pressure and mean pulse rates were compared at various intervals as- before premedication, just after pre-medication, before and after giving drug, just after induction, on intubation and intraoperatively at interval of3 min, 6 min, 9 min, 12 min, Before pneumoperitonium, 15th min during pneumoperitonium, 30th min, 45th min 60th min, after CO2 release, after extubation, immediate post-op, 15 min post-op, 30 min post-op, and then postoperatively up to 1 hour.Any other complications were also noted in both groups.Results:group B which received butorphanol as an opioid showed significantly lower mean pulse rates at post intubation 9 min, 12 min and just before pneumoperitoneum and mean arterial pressures were also significantly lower at post intubation 6 min,9min,12min and upto postpneumoperitoneum 15 min compared to group F which received fentanyl.very few patients experienced nausea and vomiting in both groups. Sedation was seen in 15 patients of group B which received butorphanol Conclusion: From the present study we conclude that the butorphanol in a dose of 1mg (repeated 0.5mg after 30min) has better haemodynamic stress reducing agent than fentany 2mcg/kg(repeated 0.5mcg/kgafter 30 min) in laparoscopic surgeries.
Authors and Affiliations
Basavaraj Patil, Shivanand L K, Vineet G
Keywords
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- EP ID EP616927
- DOI 10.26611/10151035
- Views 174
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