A Comparison of antimicrobial effect of the mouthwash containing chlorhexidine, Cetylpyridinium chloride, and zinc lactate (Halita) and chlorhexidine against Pseudomonas aeruginosa and staphylococcus aureus: in vitro study
Journal Title: Scholars Bulletin - Year 2016, Vol 2, Issue 10
Abstract
Abstract:Staphylococcus aureous and pseudomonas aeroginosa have been dedicated the attentions since its potential to create oral diseases. Therefore the control of these microorganisms can play a great role in oral health. To gain this goal there are some medical methods such as utilizing a mouthwash like chlorhexidine. Since the chlorhexidine has some side effects like changing the taste, there is a new formula of cetylpredinium (Halita) which can be an alternative to chlorhexidine. The aim of this study was to compare the antibacterial effect of chlorhexidine and Halita on reduction of Staphylococcus aureous and pseudomonas aeroginosa. In this in vitro study there were 3 groups of chlorhexidine 0.2%, chlorhexidine 0.02% and halite as for positive control, negative control and the case respectively. Each mouthwash was pure up into 5 tubes in 90 ml and then 10 ml of bacterial species (0.5 McFarland) were mixed in with a suab and after that the specimens were picked up after 5, 10, 15, 30 and 60 seconds after mixing the bacterial species. The specimens were then cultured in plates in order to count the bacterial colonies. The data were analyzed by SPSS 17. The data revealed that the chlorhexidine 0.2% has a significantly great effect on staphylococcus and Halita showed the higher effect on pseudomonas aeroginosa. Nevertheless the overall results revealed that the halite and chlorhexidine 0.2% had a statistically significant difference in reduction of the bacterial counts. The study showed that the Halita can be an alternative mouth rinse to chlorhexidine 0.2% because of its less side effects. Keywords: Staphylococcus aureous, Pseudomonas aeroginosa, Chlorhexidine, Halita.
Authors and Affiliations
Marziyeh Aghazadeh, Hosein Eslami, Hosseinsamadi kafil, Zahra Aghazadeh, Ahmad Behruzian, Paria Motahari
Keywords
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