A COMPARISON OF CLINICAL PROFILE AND PREVALENCE OF COMORBIDITIES AMONG BIOMASS AND TOBACCO SMOKE-INDUCED COPD PATIENTS AT A TERTIARY CARE CENTRE IN NORTH INDIA
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 16
Abstract
BACKGROUND Although, smoking is the most common risk factor implicated in the causation of chronic obstructive pulmonary disease (COPD), biomass smoke exposure is an important risk factor, especially in women residing in rural areas of developing countries such as India. Comorbidities are prevalent in patients with COPD because of systemic inflammation. The prevalence of comorbidities among biomass smoke-induced COPD has not been widely studied. Aims and Objectives- To assess whether patients exposed to biomass fuel have similar clinical profile and prevalence of comorbidities as smoker COPD or not. MATERIALS AND METHODS The clinical characteristics and prevalence of comorbidities were compared between 411 male patients with smoker COPD and 288 female patients with biomass smoke-induced COPD. RESULTS The patients exposed to biomass fuel were all females, were younger, had higher body mass index (BMI) and had less severe disease (higher values of post bronchodilator (BD) forced expiratory volume in the first second (FEV1 %)). The mean age in smoker COPD was significantly higher than in biomass smoke-induced COPD (p < 0.001). The mean BMI was lower in smoker COPD as compared to that in biomass smoke-induced COPD and this difference was statistically significant (p= 0.042). Coronary artery disease (CAD) (13.86% versus 3.81%, p < 0.0001) and systemic hypertension (HTN) (15.32% versus 3.47%, p < 0.0001) were significantly more common in smoker COPD without any other significant differences. Obstructive sleep apnoea (OSA), lung cancer and anaemia were found to be more common in biomass fuel-induced COPD, although not statistically significant. CONCLUSION CAD and systemic HTN were significantly more prevalent in smoker COPD.
Authors and Affiliations
Dev Singh Jangpangi, Anubhuti Singh, Jagdish Rawat, Tulsi Adhikari
Keywords
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- EP ID EP414621
- DOI 10.14260/jemds/2018/438
- Views 89
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