A comparison of the in vitro resorption rate of human amnion membrane and commercially available bovine collagen membrane for potential periodontal applications
Journal Title: IP International Journal of Periodontology and Implantology - Year 2018, Vol 3, Issue 2
Abstract
Introduction There is a dire need for a reliable substitute for the connective tissue autografts for root coverage procedures Recently human amnion membrane is increasingly being used in this regardThis study investigates the in vitro resorption rate of human amnion membrane and compares it with the resorption rate ofcommercially available bovine collagen membraneMaterials and Methods Thickness of human amnion membrane samples and bovine collagen membranes were measured The in vitro resorption tests were conducted by placing the i human amnion membrane and bovine collagen membrane of equal sizes 10 mm 5 mm in 5 ml of pH 74 phosphate buffer solution on a shaker set at 40 rpm for 4 weeks The resorption rates were expressed as the accumulated weight losses of the membranes at the end of first second third and fourth weekResults The average thickness of the amnion membranes used in this study was 46mmThe thickness of the bovine collagen membrane was 37mmAmnion membranes degraded 21 of its initial weight at the end of the first week 241at the end of second week 3135 at the end of the third week and 70 at the end of four weeksBovine collagen membranes degraded 6of its initial weight at the end of the first week 13 at the end of second week 49 at the end of the third week and 80at the end of four weeksConclusion Human amnion membranes could assist root coverage procedures since they resist complete degradation even at 4 weeksKeyword Human amnion membrane
Authors and Affiliations
Annie Kitty George, Yogesh Bharat Dalvi, Sunu Alice Cherian, Ruby Varghese
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