A cross-sectional study of most prevalent uropathogens in urinary tract infection in relation to gender and antibiotic sensitivity
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 17, Issue 2
Abstract
Introduction: Knowledge of most prevalent uropathogens in a geographic area is vital for treating physicians of that area to make a better choice of empirical antibiotics. In addition, understanding how the most prevalent uropathogens are associated with gender can be helpful to implement better preventive health initiatives to decrease the prevalence of urinary tract infection (UTI) in the susceptible gender. This study primarily aims to study the most common UTI causing uropathogens' antibiotic sensitivity pattern and their association with gender. Methods: This cross-sectional study was done retrospectively using positive urine culture reports of 140 patients tested between January 2011 to January 2014 in a tertiary care health facility in Mumbai, India. Most common uropathogens were identified and their antibiotic sensitivity and association with gender were assessed. Results: Most prevalent uropathogens were E. coli (47%), Klebsiella spp. (28%) and Pseudomonas spp. (20%). Nitrofurantoin's sensitivity to E. coli was significantly higher than the other two uropathogens. Females were more prone to UTI due to these uropathogens. Conclusion: E. coli, Klebsiella spp. and Pseudomonas spp. were the most common uropathogens. Nitrofurantoin may be considered as the empiric antibiotic of choice for UTI. Prosperous sensitivity profile of Chloramphenicol against E. coli and Klebsiella spp. requires further research for its possible usage in UTI. Public health prevention methods focused primarily toward females to control the UTI prevalence due to these uropathogens needs to be considered seriously.
Authors and Affiliations
Dr. Sumanta Saha, Dr. Anandatirth Vishnu Kulkarni2
Keywords
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- EP ID EP361570
- DOI 10.9790/0853-1702046772
- Views 86
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