A New Biochemical Marker for the Differential Diagnosis of Epileptic Seizure Types: Ischaemia-modified Albumin
Journal Title: Istanbul Medical Journal - Year 2020, Vol 21, Issue 6
Abstract
Introduction: This study aimed to evaluate the changes in ischaemia-modified albumin (IMA) levels in different types of hypoxia-associated epileptic seizures. Methods: A total of 80 patients admitted to the Neurology Outpatient Clinic in Ankara Numune Training and Research Hospital and 103 controls were included in the study. The patients were divided into two groups in terms of the seizure type, including seizures with partial and secondary generalisation and primary generalised seizures. Additionally, patients were classified in terms of the duration between the initial diagnosis and admission. The levels of IMA, albumin and uric acid were analysed by spectrophotometry and comparisons between the groups were performed. Results: IMA levels and IMA/Albumin index values were higher in the patient group than in the control group (p<0.05; p<0.01, respectively). Regarding the evaluation of the seizure types, IMA and IMA/Albumin index levels were mainly higher in patients with primary generalised seizures (p<0.05). Moreover, these parameters were significantly increased in proportion to the duration of diagnosis. Conclusion: IMA and IMA/Albumin index may enable clinicians to differentiate the types of epilepsy.
Authors and Affiliations
Arzu Kösem, Sevilay Sezer, Çiğdem Yücel, Ayşe Pınar Titiz, Zeynep Neşe Öztekin, Turan Turhan
Keywords
Related Articles
- EP ID EP691483
- DOI 10.4274/imj.galenos.2020.56659
- Views 104
- Downloads 0
Pseudoexfoliation Syndrome Prevalence in Somali Patients with Senile Cataract
Introduction: To evaluate the prevalence and demographic data of Pseudoexfoliation syndrome (PEX) in Somali patients with age-related cataract surgery. Methods: The study included 110 eyes of 110 patients planned for un...
Acute Pancreatitis Associated with Rotavirus Infection and Review of The Literature
Agents causing acute gastroenteritis are not common causes of pancreatitis etiology in children. Pancreatitis associated with rotavirus infection is very rare. Cases with acute pancreatitis during rotavirus gastroenterit...
Evaluation of Factors Affecting the Mortality and Morbidity of Patients with Acute Mesenteric Ischaemia
Introduction: Acute mesenteric ischaemia (AMI) is a disease with high mortality that is not easy to diagnose. It usually develops as a result of arterial obstructions of mesenteric vessels. In this study, we aimed to eva...
Endoscopic Approach to Esophageal Leiomyomas: Single Center Results
Introduction: Leiomyoma is the most common esophageal benign lesion. There are many treatment methods from endoscopic treatment methods to surgery in the treatment of leiomyoma. In this study, we evaluated the results of...
Is Component Separation a Safe Method in Incisional Hernias?
Introduction: Incisional hernias after abdominal surgical procedures cause morbidity, significant loss of labor and affect quality of life. In this study, we investigated whether component separation (CS) technique is a...