A New Biochemical Marker for the Differential Diagnosis of Epileptic Seizure Types: Ischaemia-modified Albumin
Journal Title: Istanbul Medical Journal - Year 2020, Vol 21, Issue 6
Abstract
Introduction: This study aimed to evaluate the changes in ischaemia-modified albumin (IMA) levels in different types of hypoxia-associated epileptic seizures. Methods: A total of 80 patients admitted to the Neurology Outpatient Clinic in Ankara Numune Training and Research Hospital and 103 controls were included in the study. The patients were divided into two groups in terms of the seizure type, including seizures with partial and secondary generalisation and primary generalised seizures. Additionally, patients were classified in terms of the duration between the initial diagnosis and admission. The levels of IMA, albumin and uric acid were analysed by spectrophotometry and comparisons between the groups were performed. Results: IMA levels and IMA/Albumin index values were higher in the patient group than in the control group (p<0.05; p<0.01, respectively). Regarding the evaluation of the seizure types, IMA and IMA/Albumin index levels were mainly higher in patients with primary generalised seizures (p<0.05). Moreover, these parameters were significantly increased in proportion to the duration of diagnosis. Conclusion: IMA and IMA/Albumin index may enable clinicians to differentiate the types of epilepsy.
Authors and Affiliations
Arzu Kösem, Sevilay Sezer, Çiğdem Yücel, Ayşe Pınar Titiz, Zeynep Neşe Öztekin, Turan Turhan
Keywords
Related Articles
- EP ID EP691483
- DOI 10.4274/imj.galenos.2020.56659
- Views 112
- Downloads 0
Baseline SUV Range for Liver and Blood Pool in Patients Undergoing F-18 Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography
Introduction: The aim of the study was to define the baseline SUVmax range in the liver and blood pool of patients undergoing fluorodeoxyglucose-positron emission tomography/computed tomography (FDG-PET/CT) imaging. Met...
Penetrating Lung Injury Caused by a Close-range Blank Cartridge: Case Report
A 17-year-old male was brought to the emergency department with chest injury by a gunshot from a blank cartridge (BC). No bullet or fragment was seen in the radiological examination. The patient underwent left thoracotom...
Is Component Separation a Safe Method in Incisional Hernias?
Introduction: Incisional hernias after abdominal surgical procedures cause morbidity, significant loss of labor and affect quality of life. In this study, we investigated whether component separation (CS) technique is a...
One-stage Combined Surgical Treatment of Spinal Deformity and Medulla Spinalis Abnormality
Introduction: Congenital spinal deformities accompanied by medulla spinalis anomalies are relatively common conditions and can lead to severe complications when left untreated. The conventional treatment approach for sev...
Appendiceal Mucocele Spontaneously Drained into the Cecum: Report of a Case
We aimed to present a case of appendiceal mucocele who was admitted with abdominal pain, operated under elective conditions and found to have been spontaneously drained from the root of the appendix to the colon in surgi...