A New Biochemical Marker for the Differential Diagnosis of Epileptic Seizure Types: Ischaemia-modified Albumin

Journal Title: Istanbul Medical Journal - Year 2020, Vol 21, Issue 6

Abstract

Introduction: This study aimed to evaluate the changes in ischaemia-modified albumin (IMA) levels in different types of hypoxia-associated epileptic seizures. Methods: A total of 80 patients admitted to the Neurology Outpatient Clinic in Ankara Numune Training and Research Hospital and 103 controls were included in the study. The patients were divided into two groups in terms of the seizure type, including seizures with partial and secondary generalisation and primary generalised seizures. Additionally, patients were classified in terms of the duration between the initial diagnosis and admission. The levels of IMA, albumin and uric acid were analysed by spectrophotometry and comparisons between the groups were performed. Results: IMA levels and IMA/Albumin index values were higher in the patient group than in the control group (p<0.05; p<0.01, respectively). Regarding the evaluation of the seizure types, IMA and IMA/Albumin index levels were mainly higher in patients with primary generalised seizures (p<0.05). Moreover, these parameters were significantly increased in proportion to the duration of diagnosis. Conclusion: IMA and IMA/Albumin index may enable clinicians to differentiate the types of epilepsy.

Authors and Affiliations

Arzu Kösem, Sevilay Sezer, Çiğdem Yücel, Ayşe Pınar Titiz, Zeynep Neşe Öztekin, Turan Turhan

Keywords

Related Articles

Vitamin D Deficiency Among Female University Students (18 to 25 years) in Spring

Introduction: In this study, the laboratory results of female university students whose vitamin D levels were requested were reviewed. Thus, it was aimed to determine the levels of vitamin D, as well as to classify it as...

Endoscopic Approach to Esophageal Leiomyomas: Single Center Results

Introduction: Leiomyoma is the most common esophageal benign lesion. There are many treatment methods from endoscopic treatment methods to surgery in the treatment of leiomyoma. In this study, we evaluated the results of...

Comparison of the Haematological and Anaesthetic Complications of Multiple Pregnancy Cases

Introduction: The frequency of caesarean delivery is increasing worldwide. Nowadays, multiple pregnancy rates are increasing significantly due to the prevalence of assisted reproductive techniques. The purpose of this re...

Prediction of Prognostic Factors in the Survival of Non-small-cell Lung Cancer Patients with Multiple Brain Metastases

Introduction: We aimed to investigate the factors affecting survival in non-small-cell lung cancer (NSCLC) patients with multiple brain metastases. Methods: One hundred thirty patients who were diagnosed with NSCLC at t...

Comparison of Fluorometric İmmunoassay and Tandem Mass Spectrometry Methods Used in the Diagnosis of Phenylalanine Metabolism Disorders in Turkish Children

Introduction: Phenylketonuria is one of the common causes of preventable mental retardation. Therefore, dietary and/or cofactor therapy initiated by early detection of the disease is of great clinical importance. In this...

Download PDF file
  • EP ID EP691483
  • DOI 10.4274/imj.galenos.2020.56659
  • Views 111
  • Downloads 0

How To Cite

Arzu Kösem, Sevilay Sezer, Çiğdem Yücel, Ayşe Pınar Titiz, Zeynep Neşe Öztekin, Turan Turhan (2020). A New Biochemical Marker for the Differential Diagnosis of Epileptic Seizure Types: Ischaemia-modified Albumin. Istanbul Medical Journal, 21(6), -. https://europub.co.uk./articles/-A-691483