" A novel and efficient synthesis of bisindolyl methanes with using silica-supported 3-(triethoxysilyl) propane-1-ammonium chloride as reusable catalyst under solvent free conditions
Journal Title: Iranian Chemical Communication - Year 2016, Vol 4, Issue 4
Abstract
A facile and efficient synthesis of bis(indolyl)methanes derivatives (3a-u) was reported via a condensation reaction of aldehydes and indole in the presence of by silica-supported-3-(triethoxysilyl) propane-1-ammonium chloride catalysis under solvent free conditions. We studied the reaction in different conditions and optimized. The use of just 0.02 g of (silica gel-ammonium salt) is sufficient. The reaction was carried out at 110 °C under thermal condition. This method, including some advantages such as mild reaction condition, easy work-up, and recoverable and reusable catalyst. A facile and efficient synthesis of bis(indolyl)methanes derivatives (3a-u) was reported via a condensation reaction of aldehydes and indole in the presence of by silica-supported-3-(triethoxysilyl) propane-1-ammonium chloride catalysis under solvent free conditions. We studied the reaction in different conditions and optimized. The use of just 0.02 g of (silica gel-ammonium salt) is sufficient. The reaction was carried out at 110 °C under thermal condition. This method, including some advantages such as mild reaction condition, easy work-up, and recoverable and reusable catalyst..
Authors and Affiliations
Mohammad Reza Poor Heravi, Aazam Monfared, Masoumeh Ahmadi
Keywords
Related Articles
- EP ID EP259691
- DOI -
- Views 108
- Downloads 0
Efficient procedure for the synthesis of quinoline derivatives by NbCl5.PEG and NbCl5 in glycerol as green solvent
Quinolines, an important class of potentially bioactive compounds, have been synthesized by treatment of O-aminoarylketones and carbonyl compounds utilizing niobium (V) chloride / polyethylenglycole(NbCl5.PEG) and niobiu...
ZrOCl2.8H2O@nano SiO2: a green and recyclable catalyst for the synthesis of benzimidazoles
ZrOCl2.8H2O@nano SiO2 has been synthesized for the first time via a simple procedure and characterized by SEM (scanning electron microscopy), FT-IR, and EDX (energy-dispersive X-ray) techniques. The efficiency of the pre...
An efficient solvent-free synthesis of 1,8-dioxo-octahydroxanthenes by using Fe2(SO4)3.7H2O as catalyst
A facile and efficient protocol for the synthesis of 1,8-dioxo-octahydroxanthenes has been developed by one-pot Knoevenagel condensation, Michael addition and cyclodehydration reaction of dimedone (active methylene carbo...
One-pot multicomponent reaction for the synthesis of 2-amino-4-chromenes promoted by 1-methyl imidazoliumiodide [mim]Cl ionic- liquid catalyst under solvent-free conditions
simple, clean, and environmentally benign three-component process for the synthesis of 2-amino-4Hchromenes using [mim]Cl, as an efficient catalyst under solvent-free conditions are described. A wide range of aromatic ald...
Synthesis of nanostructured palladium, palladium oxide and palladium-palladium oxide nanocomposite by the gel combustion method and application as catalyst of hydrogen release
This paper presents a new gel combustion method to synthesize palladium nanoparticles, palladium oxide (PdO) nanoparticles and palladium-palladium oxide nanocomposites. In the proposed method, there are some effective pa...