A PROSPECTIVE CLINICO-PATHOLOGICAL STUDY OF ORAL LESIONS AND DIAGNOSTIC CORRELATION BETWEEN BRUSH CYTOLOGY AND HISTOPATHOLOGY
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 14
Abstract
BACKGROUND Oral carcinoma is the 6th most common malignancy in western world and accounts for more than 40% cancers in the world. Normally, the standard practice to confirm the presumed clinical diagnosis is to take punch biopsy of the lesion. But exfoliative cytology being a non-invasive procedure has a better patient compliance. Aims and Objectives- To evaluate the clinical profile of the patients of oral mucosal lesions and to find the diagnostic correlation between brush cytology and histopathology of these oral mucosal lesions as well as to see the histopathological pattern of these lesions and to establish the factors which are usually causative to such malignant oral lesions. MATERIALS AND METHODS 60 cases with oral mucosal lesions were included in the study. All patients underwent oral brush cytology and punch biopsy. Sensitivity, specificity, positive and negative predictive values were calculated. Cytopathology and histopathology of the lesions were compared. RESULTS The incidences of oral cancer were very high among the age group of 42 - 50 years. Males were more affected (M: F 3.2: 1) and the most common site involved was the tongue. The sensitivity, specificity, positive and negative predictive values for malignant lesions were 92.7%, 80%, 98% and 50%. Statistical analysis showed p < 0.05, suggesting that there is significant association between brush cytology and histopathology in assessing clinically premalignant and malignant lesions. CONCLUSION Oral brush cytology is an important screening tool for early diagnosis of oral cancer and is the key factor for its effective management. The fact that it is painless, easy to perform, has better patient compliance, has high specificity in both malignant and premalignant lesions makes it an ideal screening test.
Authors and Affiliations
Aparaajita Upadhyay, Mundra R. K
Keywords
Related Articles
- EP ID EP414313
- DOI 10.14260/jemds/2018/384
- Views 97
- Downloads 0
PANCREATICO DUODENAL NEUROENDOCRINE TUMOURS – OUR EXPERIENCE OVER THE PAST 2 YEARS
[b] INTRODUCTION[/b]: Pancreaticoduodenal Neuroendocrine tumours are a heterogeneous group of tumours with their origin in neuroendocrine cells of the embryological gut which are positive for ‘Pan-neuroendocri...
NUTRITIONAL ANAEMIA AMONG CURRENTLY MARRIED FEMALES IN THE REPRODUCTIVE AGE GROUP IN RURAL JAMMU.
[b] BACKGROUND[/b]: More than one-third of world’s women are anaemic with majority residing in developing countries and that too in rural areas. The most highly affected population in the decreasing order is pre...
COMPARISON OF MATERNAL AND PERINATAL OUTCOME IN ELECTIVE REPEAT CAESAREAN SECTION DONE BEFORE 39 WEEKS AND THOSE DONE AT OR AFTER 39 WEEKS OF GESTATION
[b] INTRODUCTION[/b]: Caesarean sections are one of the commonest surgeries performed in the world today. The timing of scheduling an elective repeat cesarean section has been an issue of debates Because of inc...
PRESERVANCE OF FUNCTIONAL CAPACITY IN OSTEOARTHRITIS KNEE IN RURAL AND SEMI-URBAN POPULATION
BACKGROUND Osteoarthritis (OA), also often called ‘osteoarthrosis’ or ‘degenerative joint disease,’ is the most common form of arthritis. Prevalence of OA in India is reported to be in the range of 17 - 60.6%. Knee osteo...
EVALUATION OF ROLE OF FAST VS CECT ABDOMEN IN DETECTING ORGAN INJURY IN BLUNT ABDOMEN TRAUMA PATIENTS
BACKGROUND There is rapid increase in the number of blunt abdomen injury patients, mainly due to road traffic accidents. The physical signs are often masked in these patients and usually there is delay in the diagnosis o...