A Prospective Randomized Double Blind Study on Postoperative Pain Relief in Lower Orthopedic Surgeries-Comparison between Intravenous Inj. Nalbuphine, Inj. Tramadol and Inj. Ketorolac
Journal Title: Indian Journal of Anesthesia and Analgesia - Year 2018, Vol 5, Issue 10
Abstract
Introduction: Effective post surgical pain management is essential for the recovery and rehabilitation process. Intravenous injection brings more rapid pain relief than other methods.In this study, We had compared Inj. Nalbuphine, Inj. Tramadol and Inj. Ketorolac given intravenously for post operative pain relief in patients who underwent ower limb orthopaedic surgeries Aim: To compare the analgesic efficacy and side effects of intravenous Nalbuphine, Tramadol and Ketorolac for postoperative pain relief in patients undergoing lower limb orthopaedic surgeries under spinal anesthesia. Methodology: After obtaining informed consent and institutional ethical committee approval, 1 50 patients were randomly assigned to one of the three study groups (Group T, Group K, and Group N) based on computer generated random numbers Each group consists of 50 patients Group ‘T’ received Inj. Tramadol 2mg/kg IV Group ‘K’ received Inj. Ketorolac 0.4mg/kg IV Group ‘N’ received Inj. Nalbuphine 0.3mg/kg IV Spinal anaesthesia was performed in sitting position using 25 G spinal needle under aseptic precaution using 0.5% Bupivacaine hyperbaric solution. Intra operatively hemodynamic variables like pulse rate, Blood pressure, ECG, SpO2 monitored. 90 minutes after spinal Anaesthesia each group of patients were administered their respective drug intravenously irrespective of completion of surgery. Post operatively following parameters were monitored every hour for a period of 24 hours. 1. hemodynamics 2. Pain score 3. Sedation Score. Results: There is no significant difference in demography.The changes in hemodynamics and sedation are more in Group N than other groups. Conclusion: Nalbupine has more analgesic effect than ketorolac and tramadol with more sedation.
Authors and Affiliations
M. Karthik
Keywords
Related Articles
- EP ID EP548261
- DOI 10.21088/ijaa.2349.8471.51018.11
- Views 93
- Downloads 0
A Study on the Efficacy of Ketamine Given Intrathecallyas A Spinal Anesthetic Agent
Ketamine a phencyclidine derivative with potent analgesic properties possesses few advantages over the other local anesthetics as it tends to stimulate the cardiovascular system and maintains the respiratory response to...
Addition of Morphine to Bupivacaine in Ultrasound Guided Transversus Abdominis Plane Block Prolongs Postoperative Analgesia after Gynaecological Cancer Surgery
Background: There is significant postoperative pain in major gynecological cancer surgery patients. Ultrasound (USG) guided Transversus Abdominis Plane (TAP) block is a novel approach to provide analgesia to anterior abd...
Comparison of Dexmedetomidine and Propofol on Haemodynamics, Ionic Balance and Postop Sedation in Brachial Plexus Repair Surgery: An Entropy Guided Prospective Trial
Context: Propofol is the commonly used intravenous drug to maintain adequate depth of anaesthesia in brachial plexus repair surgery under general anaesthesia without muscle relaxant. It has rapid onset of action, a...
To Evaluate Efficacies of Dexmedetomidine and Clonidine as an Adjuvants in Epidural Anaesthesia with Ropivacaine
Aim: To evaluate efficacies of dexmedetomidine and clonidine as adjuvants to ropivacaine in Epidural Anaesthesia in patients undergoing lower limb orthopaedic surgeries. Materials and Methods: A randomized prospective s...
Prevention of Propofol Injection Pain: A Comparison between Ondansetron, Dexamethasone and Lidocaine
Introduction: Propofol (2,6 di-isopropyl phenol) is widely used agent for induction of anaesthesia, although the pain during its injection remains a concern for all anaesthesiologists. The incidence of Propofol injection...