A Prospective Study of Early Postoperative Course and Pathological Outcome of Modified D2 Gastrectomy-A Single Institute Experience
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2019, Vol 18, Issue 4
Abstract
Survival after curative surgery in advanced carcinoma is not so promising. Even after use of chemotherapy, radiation therapy the goals are not met. So it is the tumour biology which is important and the future would be probably biological therapy. Considering western data on stomach cancer molecular profile Her2neu would be promising marker for target therapy to be considered. But the fact has not been adequately tested in Indian scenario and the present study does not support routine testing of Her2neu in cases of stomach cancer considering financial aspect of Indian patient population as well as rate of its positivity in various samples of gastric cancer tissue. However, practice of individualized medicine allows it can be done in metastatic set up. As Her2neu positivity signals aggressive disease it is likely that rate of its positivity should be more in metastatic group rather than the operable gastric cancer group. Hence more studies regarding its positivity and other markers should be done in metastatic gastric cancer in Indian population particularly.
Authors and Affiliations
Dr. Subrat Kumar Sahu, Dr Durga Prasad Nanda, Dr. Syamsundar Mandal, Dr. Jayanta Chakrabarti
Keywords
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- EP ID EP574605
- DOI 10.9790/0853-1804144758.
- Views 42
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