A prospective study of effect of zinc as adjuvant therapy in acute pneumonia in children under 5 year of age
Journal Title: IP International Journal of Medical Paediatrics and Oncology - Year 2018, Vol 4, Issue 4
Abstract
Introduction It is has been observed from the work of various author that zinc deficiency is associated impaired growth and immune function Trail for evaluation of efficacy of zinc as an adjuvant to therapy in children with mild to moderate zinc deficiency has been conducted Some study has suggested that it is associated with accelerated recovery and reduced duration of hospital stay but so many trail in India have found no effect The present study was undertaken to study the effect of zinc as on adjuvant therapy in acute pneumonia beside standard antimicrobial agent in children below 5 year of ageMaterials and Methods About 116 children under five years of age were enrolled for this study based on inclusion and exclusion criteria They were grouped in to two study groups by stratified randomisation Each group consists of 55 children and 6 children were dropped from the studyResult The mean time of resolution of distress was higher in group B than group A that is 6048 VS 4842 having P value 02840 which is not significant statistically The mean duration of oxygen use was 2042 hr in group A and 3642hrs in group B with P value 04326 which is not significant Patients in group A has taken less time to become asymptomatic that is 6427 hrs versus 5273 hrs but this difference is not significant P0138006 The duration of stay of group B patients were significantly higher than group A 813 hrs vs 72hr with P value 0021274Discussion and Conclusion From our study we would like to conclude from our result that adjuvant treatment with 20 mg zinc per day along with antibiotic is associated with accelerated achievement of saturation above 90 and reduced duration of stay in hospitalKeywords Zinc Adjuvant therapy Paediatric pneumonia
Authors and Affiliations
P Suresh Babu, K Visweswara Rao, Anand Acharya
Keywords
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- EP ID EP482947
- DOI 10.18231/2581-4702.2018.0032
- Views 88
- Downloads 0
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