A Prospective Study on Clinical Profile and Angiographic Pattern of Coronary Artery Ectasia in Coronary Artery Disease Patients
Journal Title: International Journal of Medical Science and Innovative Research (IJMSIR) - Year 2019, Vol 4, Issue 7
Abstract
Introduction: Coronary artery Ectasia (CAE) has been defined as an abnormal dilatation of coronary artery, with luminal diameter exceeding 1.5 times the adjacent normal reference segment. According to the extent of involvement ectasia may be labelled as focal or diffuse. Prevalence of CAE varies from 0.3% to 6 % .The highest prevalence reported from India and Pakistan (10-12% &12.5% respectively). CAE may occur as an isolated form but most commonly seen in association with obstructive CAD . Ectasia is often viewed as a variant form of obstructive Coronary Artery Disease (CAD) and atherosclerosis is considered as a contributing factor in more than half of the cases. Although the association with atherosclerotic CAD is well evident, the relationship between traditional atherosclerotic risk factors and Ectasia remains controversial. Especially its poor correlation with Diabetes mellitus suggested Ectasia is a distinctive form of atherosclerosis characterized by positive remodeling–(Glagovian phenomenon) in contrast to obstructive disease (Negative Remodeling) .Hemodynamic factors like flow, stretch, shear stress along with inflammatory signals were proposed as the triggers for this abnormal vascular remodeling and postulated as the link between atherosclerosis and CAE in susceptible individuals. Aims & Objectives 1. To assess the prevalence of Coronary Artery ectasia in patients with CAD 2. To Analysis of Risk factors and clinical presentation of CAE and to compare it with patients having only obstructive CAD. 3. To describe the angiographic characteristics of CAE. 4. To study the influence of CAE on outcome of CAD.
Authors and Affiliations
Dr Gireesh G. K. G. K.
Keywords
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