Abstract

Background:- Alcoholic Liver Disease(ALD) is one of the leading social problem arising in the young individuals of India.It has a negative impact on both the physical,mental and economic aspects of individuals’ life. Objectives:- To study the Haematological and Biochemical profiles in 30 ALD patients and 30 controls attending KIMS Hospital, Hubballi. Materials and Method:- The present study was undertaken in ALD patients attending KIMS Hospital Medicine OPD No. 40,Hubballi. Statistical Analysis was done. Results:- The mean Hb, RBC count, Platelet count, PCV, MCHC, Total Protein and Albumin were significantly decreased while the mean MCV, TLC, Absolute neutrophil and lymphocyte count, Total and Direct Bilirubin, Liver enzymes and Derritis ratio were significantly increased in ALD patients (‘P’ value < 0.05). There were no significant changes in Lipid profile and Renal Function Test parameters.There were no significant differences (‘P’ > 0.05) in the parameters in relation to the duration they taking alcohol. There was a highly significant correlation between duration of the cases’ alcohol intake and their CAGE questionnaire score (‘P’ value < 0.01). Conclusion:-ALD is one of the leading causes of deaths,more prevalent in the males.ALD damages the liver parenchyma and deranges the blood parameters.

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