A PROSPECTIVE TRIAL COMPARING THE ACCURACY BETWEEN ULTRASOUND GUIDED FNAC OF AXILLARY LYMPH NODES AND SENTINEL LYMPH NODE BIOPSY USING METHYLENE BLUE FOLLOWED BY IMPRINT CYTOLOGY IN CLINICALLY NODE NEGATIVE EARLY BREAST CANCERS
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2019, Vol 8, Issue 10
Abstract
BACKGROUND Surgical treatment of breast cancer has evolved from Halsted’s radical mastectomy to breast conserving surgery. Similarly, surgical treatment of regional lymph nodes has also become less extensive. Axillary lymph node dissection (ALND) was standard of care for a long time and considered necessary for loco-regional control as well as for staging purpose. While ALND came with substantial morbidity and the majority of the ALND patients were “node negative”, various studies reported no effect of ALND on disease free and overall survival. In the mid-nineties the sentinel lymph node biopsy (SLNB) was introduced for staging in breast cancer patients. Conceptually, the search for sentinel lymph nodes (SLNs) in cancer patients was not new. In 1959 Gould presented his results of SLNB in patients treated for cancer of the parotid1 followed by a report describing the retrieval of SLNs in penile cancer. Two decades later Morton popularized the use of SLNB in melanoma patients. In 1994 it was Giuliano2, working in the same institute as Morton, who first described the use of the procedure in breast cancer patients. Nowadays this procedure is standard of care in clinically node negative breast cancer patients. MATERIALS AND METHODS FNA done after USG of breast and axilla followed by methylene blue injection. Blue nodes identified and harvested. RESULTS Ultrasound evaluation of node done, and suspected nodes documented. Methylene blue dye injected nodes were harvested. FNAC evaluation and imprint cytology evaluation of nodes done and compared with histopathology findings. CONCLUSION In our study, using methylene blue dye gave high accuracy in evaluation of positive lymph nodes. Imprint cytology is a useful adjuvant and is less expensive method to identify positive nodes than frozen section
Authors and Affiliations
Sivakami M.
Keywords
Related Articles
- EP ID EP555217
- DOI 10.14260/jemds/2019/147
- Views 89
- Downloads 0
ADENOID CYSTIC CARCINOMA OF THE LARYNX: AN UNIQUE PRESENTATION
A 40 year male patient presented to us with the history of having coughed out moderate quantities of blood on two occasions during the preceding week. During one episode he had coughed out a piece of tissue as well....
EFFECT OF POTASSIUM CHLORIDE AS A LOCAL ANAESTHETIC ADJUVANT FOR SUPRACLAVICULAR BRACHIAL PLEXUS BLOCK FOR UPPER LIMB SURGERIES
BACKGROUND Supraclavicular brachial plexus block is a popular and widely employed regional nerve block technique. It provides safe, effective, low cost anaesthesia along with prolonged post-operative analgesia....
A PHENOMENOLOGICAL STUDY OF PREMENSTRUAL SYMPTOMS IN MEDICAL AND NURSING STUDENTS
BACKGROUND Premenstrual symptoms are particularly common in reproductive age groups and therefore represents a significant public health problem in young girls. This study aims to estimate the prevalence, severity, deter...
A STUDY ON MAGNETIC RESONANCE IMAGING FINDINGS IN CHILDHOOD EPILEPSY
BACKGROUND Epilepsy is the most common brain disorder during childhood and it may be associated with serious conditions. Early recognition and treatment is essential for best possible outcome. MRI is the modality of choi...
EPIDEMIOLOGICAL TREND IN SUPERFICIAL FUNGAL INFECTIONS AT A TERTIARY CENTRE IN WESTERN UTTAR PRADESH, INDIA
BACKGROUND It is an indisputable fact that there is an increase in the prevalence of dermatophytosis over the past 4 - 5 years across the country (Prevalence rate= 27.6% in India and 29.6% outside India).1,2,3 However, t...