A Randomised Controlled Trial on Haemodynamic and Intraocular Pressure Changes: A Comparison between Classic Laryngeal Mask Airway and Endotracheal Intubation

Journal Title: Journal of Clinical and Diagnostic Research - Year 2019, Vol 13, Issue 2

Abstract

ABSTRACT Introduction: Laryngeal Mask Airway (LMA) and endotracheal intubation are two methods of securing airway. Insertion of airway devices causes haemodynamic and Intraocular Pressure (IOP) changes. In the present study, authors compared the two devices and the changes they cause. The mechanism of IOP rise is secondary to increased sympathetic activity. In addition, adrenergic stimulation can also produce an acute increase in IOP, by increasing the resistance to the outflow of aqueous humour in trabecular meshwork between anterior chamber and Schlemn’s canal. Aim: To compare the effects of LMA placement and endotracheal intubation on haemodynamics and IOP. Materials and Methods: Sixty patients of American Statistical Association (ASA) Status 1 or 2 undergoing general anaesthesia were included in study. They were divided into two groups, Group 1 in which classic LMA was used and Group 2, in which endotracheal tube was used. All patients were given general anaesthesia following preoxygenation. Pre-airway manipulation haemodynamics and IOP were measured followed by measurement at one, two, three minutes post airway manipulation. The change in heart rate, systolic pressure, diastolic pressure, mean pressure and IOP was calculated by subtracting the actual values from those obtained post-induction. After the surgery, when the patient was fully awake trachea was extubated or LMA was removed whichever the case may be. Results: The change in haemodynamic variables at one, two, three minutes in the intubation group was more and was statistically significant. The maximum change in haemodynamics occurred at one minute after airway manipulation. Though there was an increase in IOP in both groups, this was comparable and hence statistically not significant. The IOP in both the groups remained within the normal range even after airway manipulation. Conclusion: In a patient who can tolerate the transient haemodynamic change an endotracheal intubation should not be a contraindication when minimal changes in IOP do not matter much.

Authors and Affiliations

Madhusudan Upadya, Gaurang Kothari, Julie C R Misquith, Shishir Upadya, Snighda Raja

Keywords

Related Articles

Is Rapid Dengue Test Necessary at Primary Health Centre? A Study in Bandung City, Indonesia

ABSTRACT Introduction: Dengue is one of the most common arthropod-borne viral disease in the tropical and subtropical regions of the world. The disease is a burden in terms of morbidity, mortality and economic aspect. Th...

Standardisation and Evaluation of Direct MTT Rifampicin Tube Assay for Sputum against Smear Grading, Volume and Turnaround Time

ABSTRACT Introduction: WHO has rolled out rapid molecular methods for detection of rifampicin resistance. However, the same are not yet accessible at all the laboratories which are still dependent on alternative methods....

Prevalence and Patterns of Multimorbidity among Human Immunodeficiency Virus Positive People in Odisha, India: An Exploratory Study

Introduction: Improved and efficient Anti-Retroviral Therapy (ART) has turned HIV positive into a chronic disorder. The increase in life expectancy and quality of life comes with an increased risk of multimorbidity from...

Partial Anodontia-An Untold Clinical Presentation of Diamond Blackfan Anaemia: Case Report

ABSTRACT Diamond blackfan anaemia (DBA) is an inherited bone marrow failure syndrome characterised by severe anaemia resulting in depletion or absence of erthyroid progenitor cells and haemopoesis. The pathophysiology of...

A Study to Assess the Therapeutic Effect of Enalapril on Olanzapine Induced Metabolic Syndrome in Wistar Rats

Introduction: Metabolic Syndrome (MS) is a complex of risk factors for the development of cardiovascular complications and Type 2 Diabetes Mellitus (DM). Pharmacological management of the condition is complex, as multipl...

Download PDF file
  • EP ID EP579786
  • DOI 10.7860/JCDR/2019/38198.12528
  • Views 80
  • Downloads 0

How To Cite

Madhusudan Upadya, Gaurang Kothari, Julie C R Misquith, Shishir Upadya, Snighda Raja (2019). A Randomised Controlled Trial on Haemodynamic and Intraocular Pressure Changes: A Comparison between Classic Laryngeal Mask Airway and Endotracheal Intubation. Journal of Clinical and Diagnostic Research, 13(2), 1-4. https://europub.co.uk./articles/-A-579786