A review of 13C NMR spectra of drimane sesquiterpenes
Journal Title: Trends in Phytochemical Research - Year 2019, Vol 3, Issue 3
Abstract
Drimane sesquiterpenes are important group of phytochemicals with a wide range of medicinal properties including antibacterial, antifungal, anti-inflammatory, antioxidant, antiplasmodial, antileishmanial, molluscicidal, antifeedant and insecticidal features. Due to their wide range of medicinal activities, scientists are prompted to continuously search for novel drimane sesquiterpenes since most of the currently available anti-infective agents have drawbacks such as drug resistance and side effects. Structure determination of new compounds relies on accurate interpretation of spectroscopic data which is quite challenging but can be simplified by comparison with the data of known related compounds from the reliable databases. A large number of drimane sesquiterpenes have been examined by 13C NMR spectroscopy but such data are scattered in the literature making it hard for researchers to use them. This paper provides a review on previously reported drimane sesquiterpenes and a compilation of their 13C NMR data. It also provides a brief discussion on the substituent effect on the 13C shielding of the drimane sesquiterpenes.
Authors and Affiliations
Sylvia Awino Opiyo
Keywords
Related Articles
- EP ID EP680642
- DOI -
- Views 164
- Downloads 0
Chemical constituents of essential oil from the stem of Amomum villosum Lour
The chemical constituents of essential oil of Amomum villosum Lour stem grown in Vietnam was investigated by gas chromatography (GC-FID) and gas chromatography-mass spectrometry (GC-MS). The essential oil was obtained by...
Chemical constituents, quantitative analysis and insecticidal activities of plant extract and essential oil from Origanum onites L.
Origanum, widely used for food and pharmaceutical industry, belonging to the Lamiaceae family, is an aromatic and medicinal plant. The aerial parts of the Origanum onites L. were dried at shade and was extracted with met...
Rosa damascena essential oils: a brief review about chemical composition and biological properties
Damask rose is one of the most important aromatic plants over the world, although mostly cultivated in Bulgaria, Turkey, and Iran. Damask rose is used not only as an ornamental plant but also for extracting essential oil...
Isolation and identification of growth promoting endophytes from Artemisia annua L. and its effects on artemisinin content
Artemisinin, a sesquiterpene lactone, is a well-known antimalarial drug isolated from Artemisia annua L. (Asteraceae). Semi-synthetic derivatives of artemisinin like arteether, artemether, artesunate, etc. have also been...
Molecular simulation of polyketides isolated from the endophyte Phialophora verrucosa
Endophytic fungi are a wealth of new bioactive metabolites with vast applications in drug discovery. The methyl alcohol extract obtained from the culture of the Phialophora verrucosa Medlar., the endophytic fungus of Sen...