A REVIEW ON SYNTHESIS OF SOME N-(p-METHOXY BENZENE SULPHONYL) GLUTAMAMIDE
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2011, Vol 2, Issue 6
Abstract
Numerous studies on glutamine metabolism in cancer demonstrate that glutamic acid and glutamine analogues may be developed as possible antitumor agent. Efforts were made to synthesize glutamamide analogues, structure variants of glutamic acid and glutamine contains both the amido groups at position of glutamic acid and derivative of both glutamine and is glutamine. Glutamic acid is a natural dicarboxylic amino acid having, alone or in his derivatives, valuable antimetabolic, antimicrobial and antifungal properties. Also, this compound is considered to be useful for the future treatment of neurological conditions, ulcers, hypoglycemic coma, muscular dystrophy, epilepsy, Parkinson’s disease and mental retardation.
Authors and Affiliations
Bhaskar Banerjee , Tanushree Banerjee , Rajesh Kumar , Atul Garg , Avanish Kumar
Keywords
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