A Review on the Prevention of Aminoglycosides Induced Ototoxicity
Journal Title: Saudi Journal of Medical and Pharmaceutical Sciences - Year 2018, Vol 4, Issue 5
Abstract
Abstract:Aminoglycosides antibiotics have been in use for a long time. They are bactericidal in nature and are used to treat infections by Gram-negative bacteria. Studies have revealed their dangerous effect on human body that is the Ototoxicity. Aminoglycosides-induced ototoxicity has resulted in permanent hearing loss. Different agents are being examined for their activity against aminoglycosides-induced ototoxicity. These agents govern mostly on the principle of antioxidant capacity. Keywords: Anti-oxidants; Chelators; Cochlea; Gene therapy; Ototoxicity; Vestibular System.
Authors and Affiliations
Fatima Asghar
Keywords
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