A REVIEW ON THE THERAPEUTIC POTENTIAL OF QUINOXALINE DERIVATIVES

Journal Title: World Journal of Pharmaceutical Research - Year 2017, Vol 6, Issue 12

Abstract

Quinoxaline nucleus based derivatives have attracted researcher’s attention due to privileged and extensive applications in medicine, pharmaceuticals and pharmacological fields. Quinoxaline moiety is a part of various antibiotics such as echinomycine, levomycine, actinoleutine and also act as antiviral, anti-diabetic, anti-inflammatory, kinase inhibitors, anticancer, ion channel regulators and anti-protozoa agent. Various synthetic methodologies and strategies are developed to prepare quinoxaline compound libraries due to pivotal focal point of research activity in the field of pharmacology and medicine. In this review the substituted quinoxaline scaffolds synthetic chemistry, biological activities and applications are summarized.

Authors and Affiliations

Ali Irfan

Keywords

Related Articles

DEVELOPMENT AND EVALUATION OF PARACETAMOL SUPPOSITORIES

Suppositories are supposed to be efficient and effective dosage form specially to dispense analgesics and antipyretics. Paracetamol is widely used as antipyretic and analgesic. When used in the form of suppositories it p...

CHRONIC KIDNEY DISEASE OF MULTIFUNCTIONAL ORIGIN (CKDMFO) PREVAILING IN SRI LANKA REEVALUATED

Chronic Kidney Disease of Uncertain Aetiology seems to be caused by several factors and hence it could be best described as Chronic Kidney Disease of Multifunctional origin (CKDmfo). CKDmfo is confined to a particular ge...

MEDICINAL HERBS USED TO TREAT THE OBESITY-AN OVERVIEW

Obesity is an abnormal accumulation of body fat. Obesity is when a person is carrying too much of the body fat for their height and sex. Obesity is a major health problem and becomes an important epidemic in both develop...

SPECTROPHOTOMETRIC DETERMINATION OF HALOPERIDOL WITH 2,3 DICHLORO 5,6 DICYANO – 1,4 BENZOQUINONE

We present the validation of a developed a new spectro photometric method on a charge transfer complexation reaction. In this method, the reaction of Haloperidol with 2,3 dichloro 5,6 dicyano 1,4 benzo quinone (DDQ) in c...

IN VITRO DNA DAMAGE INHIBITION ACTIVITY OF AQUEOUS AND ETHYL ACETATE EXTRACT OF VERNONIA AMYGDALINA LEAVES

Vernonia amygdalina (Asteraceae) is a plant widely used both for nutritional and medicinal purposes throughout tropical Africa. Its health-promoting ability might be related to the effect various bioactive components of...

Download PDF file
  • EP ID EP618381
  • DOI -
  • Views 133
  • Downloads 0

How To Cite

Ali Irfan (2017). A REVIEW ON THE THERAPEUTIC POTENTIAL OF QUINOXALINE DERIVATIVES. World Journal of Pharmaceutical Research, 6(12), 47-68. https://europub.co.uk./articles/-A-618381