A SERO-EPIDEMIOLOGICAL STUDY OF HERPES SIMPLEX VIRUS- 2 ANTIBODIES AMONG PATIENTS WITH SEXUALLY TRANSMITTED INFECTIONS
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2017, Vol 6, Issue 49
Abstract
BACKGROUND Herpes genitalis (HG) is a sexually transmitted infection of great public health importance. HSV-2 is the major cause of the infection in more than 80% of such cases. Many patients with other sexually transmitted infections (STIs) without clinical signs and symptoms of HG also were found to have serological positivity for HSV-2 on serological screening for STIs. Objective- To study the seroprevalence of HSV-2 antibodies in patients with HG, ‘Other STIs’ and a cross section of the general population in the STI clinic attached to the Department of Dermatology and Venereology of Medical College, Thiruvananthapuram, one of the biggest tertiary care centre in South India. MATERIALS AND METHODS 51 patients who attended the clinic with various STIs and an equal number of individuals of the sexually active age group as a comparison group were screened for HSV-2 IgM and IgG antibodies tested by ELISA and the titres were recorded. Statistical analysis was done by an appropriate computer software and Chi-square test as a non-parametric test. RESULTS HSV-2 IgM or IgG was positive in 58.8% of STI patients, 95.2% of HG cases, 33.33% of patients with ‘other STIs’ and 27.45% of individuals of the comparison group representing the general population. CONCLUSION The HSV-2 seropositivity rates in patients with ‘other STIs’ (33.3%) and in the general population (27.5%) who in fact are patients with asymptomatic genital herpes infection, strongly indicates the necessity for screening all STI patients and vulnerable individuals of the general population to serologically screen for genital herpes infection.
Authors and Affiliations
Kavitha K, Abdul Samad K
Keywords
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- EP ID EP219092
- DOI 10.14260/Jemds/2017/808
- Views 88
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