A Short Profile On Centbucridine
Journal Title: BMH Medical Journal - Year 2014, Vol 1, Issue 4
Abstract
Almost after a century of its introduction, local anesthesia remains one of the most important methods to relieve pain in perioperative medicine. They can find their uses in different forms, i.e. as part of general anesthesia, in regional anesthesia, in plexus block or as local infiltration anesthesia itself. Many local anesthetics have been introduced since 1884, from cocaine, which was administered on eye as a local anesthetic to relatively newer drugs like ropivacaine, levo-bupivacaine, etc.; having their own advantages and disadvantages. Research always looks forward to find a drug with better safety profile in terms of cardiovascular (CV) and Central Nervous System (CNS) toxicity, with enhanced anesthetic efficiency and with increased nociceptive selectivity. Central Drug Research Institute, Lucknow, formulated a new drug called centbucridine in 1983. This new drug came into existence because of the need of a drug that offers better safety profile and less side effects.
Authors and Affiliations
Shilpi Yadav, MC Rajesh, EK Ramdas
Keywords
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